Disease

Diabetes Insipidus

About the Disease
Central Diabetes Insipidus, also known as neurogenic diabetes insipidus, is related to diabetes insipidus, neurohypophyseal and gestational diabetes insipidus. An important gene associated with Central Diabetes Insipidus is AVP (Arginine Vasopressin), and among its related pathways/superpathways are Aquaporin-mediated transport and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. The drugs Tolvaptan and Midazolam have been mentioned in the context of this disorder. Affiliated tissues include pituitary, hypothalamus and brain, and related phenotypes are failure to thrive and dehydration

Common Targets
AVP | AVPR1A | OPRK1 | OPRM1 | KCNJ16 | AVPR1B | NR1I2 | AVPR2 | CA7 | OXT | WFS1 | SLC14A2 | CA9 | CA2 | HTR2C | OXTR | Vasopressin V1 Receptor (nonspecified subtype)

疾病靶点研报
Diabetes Insipidus

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