Diabetes Insipidus

About the Disease
Central Diabetes Insipidus, also known as neurogenic diabetes insipidus, is related to diabetes insipidus, neurohypophyseal and gestational diabetes insipidus. An important gene associated with Central Diabetes Insipidus is AVP (Arginine Vasopressin), and among its related pathways/superpathways are Aquaporin-mediated transport and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. The drugs Tolvaptan and Midazolam have been mentioned in the context of this disorder. Affiliated tissues include pituitary, hypothalamus and brain, and related phenotypes are failure to thrive and dehydration

Common Targets
AVP | AVPR1A | OPRK1 | OPRM1 | KCNJ16 | AVPR1B | NR1I2 | AVPR2 | CA7 | OXT | WFS1 | SLC14A2 | CA9 | CA2 | HTR2C | OXTR | Vasopressin V1 Receptor (nonspecified subtype)

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Other Diseases

Giant Axonal Neuropathy | Granular Corneal Dystrophy | Hyperlipidemia | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Adenoma, Pituitary | T-cell Chronic Lymphocytic Leukemia | Hepatitis D | Wolcott-Rallison Syndrome | Familial Dysautonomia | Joubert Syndrome 2 | Neurodegeneration With Brain Iron Accumulation | Spinocerebellar Ataxia Type 15 | Agranulocytosis | DOCK8 Immunodeficiency Syndrome | Congenital Sodium Diarrhea | Autonomic Neuropathy | Carcinoid Tumor | Dominant Optic Atrophy | Facioscapulohumeral Muscular Dystrophy Type 1 | Charcot-Marie-Tooth Disease, Type 2C | Gigantism | Actinomycetoma | Brooke-Spiegler Syndrome | Waardenburg Syndrome Type 2A | Pheochromocytoma | Glutaric Aciduria Type 3 | Fibronectin Glomerulopathy | Pelizaeus-Merzbacher Disease | Pyloric Stenosis, Infantile Hypertrophic | Rett Syndrome | Kidney Stones | Neutropenia | Lymphomatoid Granulomatosis | Irritable Bowel Syndrome | Eiken Syndrome | Arthrogryposis | Achondrogenesis | Intestinal Tuberculosis | Torticollis | Myoclonic Epilepsy With Ragged Red Fibers | Ghosal Syndrome | Sialidosis Type I | Pleurisy | Craniopharyngioma | Von Willebrand Disease | Episodic Ataxia Type 1 | Geleophysic Dysplasia | Oculocutaneous Albinism Type 4 | Androgenic Alopecia | Sarcoidosis | Congenital Generalized Lipodystrophy | Basal Ganglia Disease | Ocular Albinism Type 1 | Myofibromatosis | Burn-McKeown Syndrome | Bietti Crystalline Dystrophy | Congenital Bile Acid Synthesis Defect | Glaucoma | Corneal Neovascularization | Bloom Syndrome | Kaposiform Hemangioendothelioma | Ehlers-Danlos Syndrome | Esophageal Motility Disorders | Common Cold | Spondylocarpotarsal Synostosis Syndrome | Schistosomiasis Mansoni | Fuchs Heterochromic Iridocyclitis | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Neurofibromatosis-Noonan Syndrome | Spina Bifida | Lennox-Gastaut Syndrome | Pseudoachondroplasia | Mannosidase Deficiency Diseases | Myoclonic Atonic Epilepsy | Cutis Laxa | Lymphoma, Mantle Cell | Meningioma | Enlarged Vestibular Aqueduct | Retinal Dystrophy | Nance-Horan Syndrome | Hydrocephalus | Neutrophilia | Iron Overload | Autoimmune Polyendocrinopathy Syndrome Type I | Angiomyolipoma | Adenocarcinoma | Beta-Propeller Protein-associated Neurodegeneration | Polyradiculopathy | Pneumonia, Viral | Stevens-Johnson Syndrome | Tinea | L-2-Hydroxyglutaric Aciduria | Chorea | Blepharitis | Renal-hepatic-pancreatic Dysplasia | Neurodevelopmental Disorders | Fascioliasis | Wiskott-Aldrich Syndrome | Hydrocephalus, Normal Pressure | Neurocutaneous Syndromes | Hypoproteinemia, Hypercatabolic | Clouston Hidrotic Ectodermal Dysplasia | Optic Nerve Hypoplasia, Bilateral | Sorsby Fundus Dystrophy | Pneumonia, Bacterial | Creutzfeldt-Jakob Disease | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Opisthorchiasis | Cranial Nerve Disease | H Syndrome | Ataxia-ocular Apraxia 2 | Porphyria, Variegate | Epidermolysis Bullosa | Spinocerebellar Ataxia Type 3 | Cardiomyopathy, Dilated, 1L | Wolfram Syndrome | Scapuloperoneal Myopathy, X-linked Dominant | Pneumothorax | Woodhouse-Sakati Syndrome | Pemphigoid | Rhabdomyosarcoma | Infantile Spasm | Urolithiasis | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Vascular Cognitive Impairment | Pseudohypoparathyroidism Type 2 | Glaucomatocyclitic Crisis | Antley-Bixler Syndrome | Papillorenal Syndrome | Congestive Heart Failure | Cartilage Disorders | Gastric Atrophy | Multiple Hamartoma Syndrome | Kaposi Sarcoma | CEDNIK Syndrome | Waldenstrom Macroglobulinemia | Leigh Syndrome | Holoprosencephaly | Keratosis, Seborrheic | Open-angle Glaucoma | Vitreoretinal Degeneration, Snowflake Type | Pierre Robin Syndrome | Glutaric Aciduria Type 1 | Schamberg Disease | Dyggve-Melchior-Clausen Disease | Craniometaphyseal Dysplasia | Sclerocornea | Hyper IgE Syndrome | Incontinentia Pigmenti | Warsaw Breakage Syndrome | Leukoplakia | Dementia | Congenital Hereditary Endothelial Dystrophy Type I | Congenital Heart Block | Spondylolisthesis | Autosomal Recessive Spastic Paraplegia Type 35 | Danon Disease | Bronchitis | Hemimegalencephaly | McCune-Albright Syndrome | IgA Nephropathy | Aplasia Cutis Congenita | Spinocerebellar Ataxia Type 23 | Noonan Syndrome-like Disorder With Loose Anagen Hair | CHARGE Syndrome | Avellino Corneal Dystrophy | Micropenis | Tyrosine Hydroxylase Deficiency | Leber Congenital Amaurosis | Osteoarthritis | Desbuquois Syndrome | Atopic Dermatitis | Norrie Disease | Inborn Errors Of Metabolism | Anti-NMDA Receptor Encephalitis | Cryptosporidiosis | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Polycystic Ovary Syndrome | Porencephaly | Wolfram Syndrome 2 | Alstrom Syndrome | Paroxysmal Kinesigenic Dyskinesia | Lamellar Ichthyosis | Spinocerebellar Ataxia Type 13 | Histiocytosis | Heroin Dependence | 3-methylglutaconic Aciduria Type I | C3 Glomerulonephritis | Olmsted Syndrome | Leprosy | Glycogen Storage Disease Type 3 | X-linked Creatine Transporter Deficiency | Cerebrotendinous Xanthomatosis | Leukocyte Adhesion Deficiency Type 1 | Chronic Granulomatous Disease | Pneumococcal Meningitis | Lymphoproliferative Disorders | Neurofibroma, Plexiform | Learning Disability | Osteogenesis Imperfecta Type III | Pseudo-pseudohypoparathyroidism | Glycogen Storage Disease Type 1 | Malonyl-CoA Decarboxylase Deficiency | Pleural Tuberculosis | Pilomatrix Carcinoma | Aplastic Anemia | Fibromuscular Dysplasia | Osteogenesis Imperfecta Type I | Adams-Oliver Syndrome | Galactosemia | Imerslund-Grasbeck Syndrome | Venous Insufficiency | Craniofacial Dysostosis | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Cardiomyopathy, Hypertrophic | Goldenhar Syndrome | Allan-Herndon-Dudley Syndrome | Stargardt Disease | Basal Cell Nevus Syndrome | Usher Syndrome Type II | Polydactyly | Hypertension, Renal | Benign Familial Infantile Seizures | Hyperinsulinism-hyperammonemia Syndrome | Thalassemia | Polymicrogyria | Cholelithiasis | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Sensorineural Hearing Loss | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Tangier Disease | Uremic Pruritus | Hypertrophy | Neuroendocrine Cancer | Carpenter Syndrome | Benign Familial Pemphigus | Cellulitis | Thrombotic Microangiopathy | Scleroderma | Aneurysm, Abdominal Aortic | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Protein C Deficiency | Bernard-Soulier Syndrome | Amelanotic Melanoma | Retinal Vasculitis | Avian Influenza | Central Pain Syndrome | Beckwith-Wiedemann Syndrome | Cholestasis | Liver Failure | Charcot-Marie-Tooth Disease Type 2T | IMAGe Syndrome | Nicotine Addiction | Diabetic Nephropathy | Congenital Aniridia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Superficial Spreading Melanoma | Blue Nevus | Usher Syndrome Type IIC | Mood Disorder | Systemic Lupus Erythematosus | Loeys-Dietz Syndrome | Diabetic Macular Edema | Hypothalamic Obesity | Creatine Deficiency Syndrome | Acrodysostosis | Angioedema, Acquired | Odonto-onycho-dermal Dysplasia | Alpha-1 Antitrypsin Deficiency | Steel Syndrome | Epidermolytic Ichthyosis, Annular | Conn Syndrome | Persistent Hyperplastic Primary Vitreous | X-linked Charcot-Marie-Tooth Disease | X-linked Acrogigantism | Hypogammaglobulinemia | Juvenile Hyaline Fibromatosis | Neurofibroma | Congenital Mirror Movements | Spinocerebellar Ataxia Type 8 | Herpes Simplex Dermatitis | Plasmacytoma | Neuroleptic Malignant Syndrome | Periodic Limb Movement Disorder | Familial Mediterranean Fever | Small Lymphocytic Lymphoma | Epidermolysis Bullosa Simplex | Sengers Syndrome | Primary Cutaneous Amyloidosis | Lattice Corneal Dystrophy Type 1 | Progressive Osseous Heteroplasia | Pitt-Hopkins Syndrome | Progressive Myoclonic Epilepsy | Short-chain Acyl-CoA Dehydrogenase Deficiency | Pseudohypoparathyroidism Type 1A | Pseudohypoparathyroidism Type 1B | Beare-Stevenson Syndrome | Renal Hypouricemia | Trachoma | Blepharospasm | Bardet-Biedl Syndrome | Anorexia Nervosa | Lipid Storage Myopathy | Molybdenum Cofactor Deficiency | Presbycusis | Meleda Disease | Optic Nerve Diseases | N-acetylglutamate Synthase Deficiency | Arthropathy | Proteus Syndrome | Cousin Syndrome | Polycythemia | Cenani-Lenz Syndactyly Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | Microphthalmia | Vitamin D Deficiency | Hyperacusis | Cherubism | Alopecia | Unverricht-Lundborg Syndrome | Arteriosclerosis | Nephrotic Syndrome Type 1 | Hyperuricemic Nephropathy, Familial Juvenile | Neurodermatitis | Takayasu's Arteritis | Dystonia | Peters-plus Syndrome | Nicolaides-Baraitser Syndrome | Thyrotoxic Periodic Paralysis | HIBCH Deficiency | Budd-Chiari Syndrome | Pontocerebellar Hypoplasia Type 7 | Onchocerciasis | Hennekam Lymphangiectasia-lymphedema Syndrome | Cranioectodermal Dysplasia | Focal Dermal Hypoplasia | Absence Epilepsy | Corneal Dystrophy And Perceptive Deafness | Ulcerative Colitis | Kindler Syndrome | Epilepsy Of Infancy With Migrating Focal Seizures | Myosin Storage Myopathy | Erythrokeratodermia Variabilis | Acute Lymphocytic Leukemia | Ganglioneuroma | Nestor-Guillermo Progeria Syndrome | Chronic Periodontitis | Glioblastoma | Insulinoma | Hereditary Pyropoikilocytosis | Neuronal Ceroid Lipofuscinosis | Lewy Body Dementia | Liver Failure, Acute Infantile | Tricho-hepato-enteric Syndrome | Myositis | Pycnodysostosis | Mucormycosis | Sleep Disorder | Perivascular Epithelioid Cell Tumor | Gestational Trophoblastic Disease | Megalencephaly | Mitochondrial Cytopathy | Raynaud Phenomenon | Congenital Absence Of Vas Deferens | Amyotrophic Lateral Sclerosis, Juvenile | Cholangitis | Asthma | Hemangioendothelioma | Skin Carcinoma | Cirrhosis | MIRAGE Syndrome | Marinesco-Sjogren Syndrome | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Menkes Disease | Acromicric Dysplasia | Primary Progressive Aphasia | Hyperparathyroidism-jaw Tumor Syndrome | Bone Marrow Necrosis | Progressive Familial Intrahepatic Cholestasis Type 3 | Malignant Peripheral Nerve Sheath Tumor | Osmotic Demyelination Syndrome | Myelomeningocele | Benign Familial Neonatal Convulsions | Cole-Carpenter Syndrome | Gyrate Atrophy Of The Choroid And Retina | Congenital Dyserythropoietic Anemia | Spinocerebellar Ataxia Type 27 | Duchenne Muscular Dystrophy | Agoraphobia | Chordoma | Asphyxia Neonatorum | Camurati-Engelmann Disease | Muscle Wasting | Encephalopathy, Hepatic | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Hemangioblastoma | Takotsubo Cardiomyopathy | Leri-Weill Dyschondrosteosis | Keratitis | Hypersensitivity