Cartilage Disorders

About the Disease
Cartilage Disease, also known as cartilage diseases, is related to multiple epiphyseal dysplasia and achondroplasia, and has symptoms including back pain, muscle cramp and sciatica. An important gene associated with Cartilage Disease is COL10A1 (Collagen Type X Alpha 1 Chain), and among its related pathways/superpathways are ERK Signaling and Collagen chain trimerization. The drugs Glucosamine and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include cartilage, bone marrow and bone, and related phenotypes are limbs/digits/tail and growth/size/body region

Common Targets
EXT1 | FGFR1 | Melanin | CANX | G3569 | DYRK1A | ADAMTS5 | GSK3B | Reverse transcriptase (Telomerase) | G7124 | G7015 | JAK2 | IL-6 receptor | MMP13 | JAK1 | JAK3 | SIK2 | RMRP | Janus Kinase (nonspecified subtype) | MIR449A | ALB | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | FGFR2 | COMP | ACE | PTGER2 | TYK2 | FGFR3 | ESR2

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