Adenosine Deaminase Deficiency

About the Disease
Adenosine Deaminase Deficiency, also known as ada deficiency, is related to severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-negative, nk cell-negative, due to adenosine deaminase deficiency and severe combined immunodeficiency, x-linked. An important gene associated with Adenosine Deaminase Deficiency is ADA (Adenosine Deaminase), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Metabolism of nucleotides. The drugs Busulfan and Antineoplastic Agents, Alkylating have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and lymph node, and related phenotypes are failure to thrive and sinusitis

Common Targets
ADAT1 | ADA | Adenosine deaminase (nonspecified subtype) | ADA2

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