Giant Cell Glioblastoma

About the Disease
Giant Cell Glioblastoma, also known as monstrocellular sarcoma, is related to glioma susceptibility 1 and sarcoma, and has symptoms including headache and seizures. An important gene associated with Giant Cell Glioblastoma is MSH2 (MutS Homolog 2), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and ERK Signaling. The drugs Sargramostim and Molgramostim have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and endothelial, and related phenotypes are Decreased viability and Decreased viability

Common Targets
G673 | MGMT

Note: If you'd like to get a target analysis report for Giant Cell Glioblastoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Giant Cell Glioblastoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Papilledema | Neurodermatitis | Pyelonephritis | Neuroblastoma | Reticular Dysgenesis | Intracerebral Hemorrhage | Polyarteritis Nodosa | Lichen Sclerosus | Non-epidermolytic Palmoplantar Keratoderma | Liddle Syndrome | Graves Disease | Klinefelter Syndrome | Demyelinating Diseases | Hypokalemia | Hemorrhagic Disorders | Diabetes Insipidus | Blepharo-cheilo-odontic Syndrome | Ophthalmia, Sympathetic | Lymphomatoid Granulomatosis | Glucagonoma | Antisynthetase Syndrome | Agranulocytosis | Weill-Marchesani Syndrome | Fowler's Syndrome | Infertility, Male | Creatine Deficiency Syndrome Due To AGAT Deficiency | Pontocerebellar Hypoplasia Type 2 | Chondrodysplasia Punctata 2, X-linked Dominant | Primary Hyperoxaluria Type 3 | Narcolepsy | Atelosteogenesis Type 1 | Guttate Psoriasis | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Cushing Syndrome | Cancer, Bladder | Motor Neuron Diseases | Split Hand-foot Malformation | Cleidocranial Dysplasia | Hyperparathyroidism, Primary | Fukuyama Congenital Muscular Dystrophy | Neurofibromatosis-Noonan Syndrome | Heroin Dependence | Amish Infantile Epilepsy Syndrome | Dementia, Vascular | Glycogen Storage Disease Type 5 | Necrobiosis Lipoidica | Keratosis | Apert Syndrome | Corneal Dystrophy | Cholangitis | Dominant Optic Atrophy | Castleman Disease | Dentinogenesis Imperfecta | Beckwith-Wiedemann Syndrome | Hyperthermia, Malignant | Hereditary Folate Malabsorption | Spinocerebellar Ataxia Type 6 | Thalassemia, Beta | Chudley-McCullough Syndrome | Encephalitis | Down Syndrome | Amebiasis | Mitochondrial Myopathy | Renal Dysplasia | Pierpont Syndrome | Osteogenesis Imperfecta Type V | Primary Hyperoxaluria | Pulmonary Veno-occlusive Disease | Spinocerebellar Ataxia Type 16 | Burn-McKeown Syndrome | Basal Ganglia Cerebrovascular Disease | Unverricht-Lundborg Syndrome | Meconium Ileus | Gastritis | Aldosterone Deficiency | Arthritis | Menetrier Disease | Cryptococcal Meningitis | Congenital Heart Defects | Epidermal Nevus Syndrome | Pseudohypoparathyroidism Type 1B | Steel Syndrome | Auriculocondylar Syndrome | Duane Retraction Syndrome | Leiomyoma | Endometriosis | Astrocytoma, Anaplastic | Primary Progressive Aphasia | Mumps | Obsessive-compulsive Disorder | Deafness, Dystonia, And Cerebral Hypomyelination | Acute Lung Injury | Lichen Planus | POEMS Syndrome | Pleural Tuberculosis | Best Macular Dystrophy | Central Core Disease | Thin Basement Membrane Disease | Kabuki Syndrome | Kabuki Syndrome 2 | Disseminated Superficial Actinic Porokeratosis | Thrombocytopenia | Seizures-scoliosis-macrocephaly Syndrome | Benign Familial Neonatal Convulsions | Chronic Granulomatous Disease | Wolfram Syndrome | Alpers Syndrome | Generalized Epilepsy With Febrile Seizures Plus | Epilepsy Of Infancy With Migrating Focal Seizures | Pemphigus Vulgaris | Synovitis | Acute Leukemia | Chorea-acanthocytosis | Progressive Familial Intrahepatic Cholestasis | Cholelithiasis | Neurotoxicity | Distal Myopathy | Purpura | Immunoproliferative Disorders | DiGeorge Syndrome | Nestor-Guillermo Progeria Syndrome | Avian Influenza | Long QT Syndrome Type 2 | Kidney Stones | Holt-Oram Syndrome | Idiopathic Multicentric Castleman Disease | Multiple System Atrophy | Neurofibromatosis Type 2 | Neuropathy | Acromesomelic Dysplasia | Pituitary Disorders | Distal Myopathy 2 | Subacute Sclerosing Panencephalitis | Milk Allergy | Chylothorax, Congenital | Pontocerebellar Hypoplasia Type 7 | Progressive Osseous Heteroplasia | Congenital Heart Block | Arteriosclerosis | Rothmund-Thomson Syndrome | Situs Inversus | Traboulsi Syndrome | Osteoporosis, Postmenopausal | Impulse Control Disorder | Facioscapulohumeral Muscular Dystrophy Type 1 | Fibrosarcoma | Papillorenal Syndrome | Coenzyme Q10 Deficiency | Methylmalonic Acidemia | Scapuloperoneal Myopathy, X-linked Dominant | Usher Syndrome Type IIC | Carey-Fineman-Ziter Syndrome | Spinocerebellar Ataxia Type 31 | Cat Eye Syndrome | Evans Syndrome | Sertoli Cell-only Syndrome | Crimean-Congo Hemorrhagic Fever | Endocarditis | Major Depression | Juvenile Hyaline Fibromatosis | Cholestasis | Phenylketonuria | Supravalvular Aortic Stenosis | Congenital Dyserythropoietic Anemia Type 4 | Pompe Disease | Autoimmune Polyendocrine Syndrome | Retinal Telangiectasia | Tinea | Adams-Oliver Syndrome | Schindler Disease | Autism | Congenital Stromal Corneal Dystrophy | Ectodermal Dysplasia | Bone Giant Cell Tumor | Beta-Propeller Protein-associated Neurodegeneration | Sick Sinus Syndrome | Encephalopathy, Hepatic | VACTERL/VATER Association | Isobutyryl-CoA Dehydrogenase Deficiency | Pernicious Anemia | Congenital Stationary Night Blindness | Non-Langerhans Cell Histiocytosis | Avellino Corneal Dystrophy | Maternally Inherited Diabetes And Deafness | Congenital Adrenal Hyperplasia 1 | Light Chain Amyloidosis | Osteogenesis Imperfecta Type II | Coffin-Siris Syndrome | Splenomegaly | Keratosis, Actinic | TARP Syndrome | Reye Syndrome | Prolymphocytic Leukemia | Meckel-Gruber Syndrome | Melanoma | Diabetes Mellitus, Transient Neonatal | Smoldering Myeloma | Colitis, Lymphocytic | Asthma, Exercise-induced | Protein C Deficiency | Congenital Dysfibrinogenemia | Conjunctivitis | Peyronie's Disease | Restless Legs Syndrome | Alagille Syndrome | Neuromyotonia | Histoplasmosis | Asphyxia Neonatorum | Glaucomatocyclitic Crisis | Basan Syndrome | Goldenhar Syndrome | Glycogen Storage Disease Type 0 | Idiopathic Pulmonary Fibrosis | Renal Failure | Measles | Esotropia | Lymphoma, Mantle Cell | Parkinson Disease 6, Autosomal Recessive Early-onset | Pituitary Dwarfism | Addison Disease | Dyslipidemia | Hereditary Spastic Paraplegia | Disseminated Intravascular Coagulation | Periventricular Nodular Heterotopia | Pulverulent Zonular Cataract | Alexander Disease | Multiple Sclerosis, Secondary Progressive | Filariasis | Multifocal Motor Neuropathy | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Dysgerminoma | Tyrosinemia Type 1 | Dysplastic Nevus | Congenital Hypofibrinogenemia | Empyema | Bloom Syndrome | Central Retinal Artery Occlusion | Pelvic Inflammatory Disease | Mosaic Variegated Aneuploidy Syndrome 2 | Cervicitis | Dermatofibrosarcoma | Vitamin B12 Deficiency | Aicardi-Goutieres Syndrome | Silver-Russell Syndrome | Alpha-1 Antitrypsin Deficiency | Gilbert Syndrome | Huntington's Disease-like 2 | Fatty Aldehyde Dehydrogenase Deficiency | Localized Scleroderma | Pouchitis | Leukoplakia, Oral | Wiskott-Aldrich Syndrome | Spondylolisthesis | Corticobasal Syndrome | Moyamoya Disease | Pancreatitis | Acute Motor Axonal Neuropathy | Familial Isolated Hyperparathyroidism | Hemoglobinopathies | Eating Disorder | Renpenning Syndrome | Fuchs Heterochromic Iridocyclitis | Spinocerebellar Ataxia Type 23 | Hypotrichosis | Aarskog-Scott Syndrome | Actinomycetoma | Leigh Syndrome | Leri-Weill Dyschondrosteosis | Pemphigoid | Acrodermatitis Enteropathica | Erythromelalgia | Pineoblastoma | Multiple Myeloma | Haim-Munk Syndrome | Chromosome 16p11.2 Deletion Syndrome | Eccrine Porocarcinoma | Dermatomyositis | Kleine-Levin Syndrome | Dystonia | Greig Cephalopolysyndactyly Syndrome | Short-chain Acyl-CoA Dehydrogenase Deficiency | Smith-Lemli-Opitz Syndrome | Diffuse Intrinsic Pontine Glioma | Juvenile Myelomonocytic Leukemia | Bardet-Biedl Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Cutaneous Mastocytosis | Cerebellofaciodental Syndrome | Niemann-Pick Disease, Type B | Holoprosencephaly | Silicosis | Genee-Wiedemann Syndrome | Hyperferritinemia-cataract Syndrome | Nance-Horan Syndrome | Pure Red Cell Aplasia | 3-M Syndrome | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Hemochromatosis | Ebstein Anomaly | Prostatitis | KBG Syndrome | Creutzfeldt-Jakob Disease | Myhre Syndrome | Mohr-Tranebjaerg Syndrome | Carcinoma, Signet Ring Cell | Chylomicron Retention Disease | Ileitis | Distal Spinal Muscular Atrophy | Thrombocythemia, Essential | Hyperparathyroidism-jaw Tumor Syndrome | Mabry Syndrome | Ectrodactyly | Left Ventricular Noncompaction | Trichotillomania | Congenital Central Hypoventilation Syndrome | Oligodendroglioma | Cold-induced Sweating Syndrome | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Hepatic Veno-occlusive Disease | Neurodegeneration With Brain Iron Accumulation | Astigmatism | Cyclic Vomiting Syndrome | Congenital Hemolytic Anemia | Bicuspid Aortic Valve | Renal Tubular Dysgenesis | Polymicrogyria | Premenstrual Syndrome | Uremia | Dwarfism | Lattice Corneal Dystrophy | Joubert Syndrome | GLUT1 Deficiency Syndrome | Lymphoproliferative Disorders | Pleomorphic Xanthoastrocytoma | Malignant Fibrous Histiocytoma | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Macular Degeneration | Hepatorenal Syndrome | Dystonia Musculorum Deformans | Galactosemia | Esophageal Motility Disorders | Hyperkeratosis | Rosacea | Usher Syndrome | Subcortical Band Heterotopia | Ichthyosis, X-linked | Myosin Storage Myopathy | Pulmonary Sclerosing Hemangioma | Zimmermann-Laband Syndrome | Ectopia Lentis, Isolated, Autosomal Recessive | Sarcoma, Ewing | Aspartylglycosaminuria | Familial Exudative Vitreoretinopathy | Carbonic Anhydrase VA Deficiency | Dubin-Johnson Syndrome | Mandibuloacral Dysplasia With Type A Lipodystrophy | Vertebrobasilar Insufficiency | Cerebral Amyloid Angiopathy | Retinal Coloboma | Brugada Syndrome 1 | Pityriasis Rubra Pilaris | Mucolipidosis Type IV | Eosinophilia | Spinal Muscular Atrophy | Chromosome 17q21.31 Deletion Syndrome | Stiff-man Syndrome | Dupuytren Disease | Cherubism | Spondylocostal Dysostosis | Hepatitis, Alcoholic | Sclerosing Cholangitis | Pulmonary Alveolar Microlithiasis | Hyperthyroidism | Opisthorchiasis | Leber Hereditary Optic Neuropathy | Posterior Polar Cataract | Spinocerebellar Ataxia Type 42 | Pelizaeus-Merzbacher Disease | Hairy Cell Leukemia | Angioimmunoblastic T-cell Lymphoma | HIBCH Deficiency | Pigment Dispersion Syndrome | Metachondromatosis | Borderline Personality Disorder | Antenatal Bartter Syndrome Type 1 | Spinocerebellar Ataxia Type 15 | Tricho-hepato-enteric Syndrome | Vitamin K Deficiency | Schistosomiasis Mansoni | Lymphoproliferative Disease, X-linked | Epidermolysis Bullosa Acquisita | Lafora Disease | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Loeys-Dietz Syndrome | Nicotine Addiction | Congenital Nephrotic Syndrome | Sickle Cell Anemia | Persistent Hyperplastic Primary Vitreous | Coffin-Lowry Syndrome | Analgesia