Gyrate Atrophy Of The Choroid And Retina

About the Disease
Gyrate Atrophy of Choroid and Retina, also known as gyrate atrophy, is related to macular retinal edema and macular dystrophy, dominant cystoid. An important gene associated with Gyrate Atrophy of Choroid and Retina is OAT (Ornithine Aminotransferase), and among its related pathways/superpathways are Regulation of expression of SLITs and ROBOs and Visual phototransduction. The drugs Ornithine and Pyridoxine have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and spinal cord, and related phenotypes are progressive visual loss and myopia

Common Targets
OAT | RPE65

Note: If you'd like to get a target analysis report for Gyrate Atrophy Of The Choroid And Retina, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Gyrate Atrophy Of The Choroid And Retina at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hypoglycemia | Gerodermia Osteodysplastica | Osteomyelitis | Acute Lung Injury | Empyema | Calcium Pyrophosphate Deposition Disease | Esophagitis | Antley-Bixler Syndrome | Spinocerebellar Ataxia Type 13 | Succinic Semialdehyde Dehydrogenase Deficiency | Thalassemia | Ectopia Lentis, Isolated, Autosomal Recessive | Woodhouse-Sakati Syndrome | Hereditary Pyropoikilocytosis | Intestinal Obstruction | Arthritis, Psoriatic | Nance-Horan Syndrome | Vertigo | Leishmaniasis, Visceral | Anorectal Malformations | Pneumothorax | Leukocyte Adhesion Deficiency | Oculocutaneous Albinism | Congenital Primary Aphakia | Ghosal Syndrome | Hereditary Spherocytosis | Granular Corneal Dystrophy Type 1 | Beare-Stevenson Syndrome | Gastritis, Atrophic | Amebiasis | Autosomal Recessive Bestrophinopathy | Fontaine Progeroid Syndrome | Barrett Esophagus | Thyroid Dysgenesis | Enhanced S-cone Syndrome | Usher Syndrome Type I | Pseudomyxoma Peritonei | Spastic Paraplegia Type 7 | Dermatomyositis | Dentinogenesis Imperfecta | Colitis, Lymphocytic | Acquired Partial Lipodystrophy | Epidermal Nevus Syndrome | Hypobetalipoproteinemias | Cholecystitis | Acute Coronary Syndrome | Spondylocostal Dysostosis | Thyroid Hormone Resistance | Robinow Syndrome | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Analgesia | Guanidinoacetate Methyltransferase Deficiency | Carcinoma, Signet Ring Cell | Cancer, Skin | Amyotrophic Lateral Sclerosis | Alpers Syndrome | Optic Neuritis | Nephroblastoma | Patent Ductus Arteriosus | Trichothiodystrophy | Androgen Insensitivity | Aplasia Cutis Congenita | Basan Syndrome | Papillon-Lefevre Syndrome | Osteosclerosis | Osteogenesis Imperfecta Type IV | Craniometaphyseal Dysplasia | Retinitis Pigmentosa | Restless Legs Syndrome | Retinopathy Of Prematurity | Hereditary Spastic Paraplegia | Ichthyosis Hystrix, Curth-Macklin Type | Diastrophic Dysplasia | Chronic Granulomatous Disease, X-linked | Cancer, Colon | Richter's Syndrome | Hemorrhagic Disorders | Polymyalgia Rheumatica | Ophthalmoplegia | Opisthorchiasis | Measles | Spinocerebellar Ataxia Type 28 | Barakat Syndrome | Vulvovaginitis | TARP Syndrome | Vitamin K Deficiency | Coffin-Lowry Syndrome | Encephalocele | Epithelial-myoepithelial Carcinoma | Cryoglobulinemia | Exotropia | Progressive Encephalopathy-optic Atrophy Syndrome | Dubin-Johnson Syndrome | Sitosterolemia | Coloboma | Congenital Afibrinogenemia | Bladder Exstrophy | Herpes Genitalis | Potocki-Shaffer Syndrome | Benign Hereditary Chorea | Hyperkalemic Periodic Paralysis | Kawasaki Disease | Micro Syndrome | Frontometaphyseal Dysplasia | Retinal Vasculitis | Disseminated Intravascular Coagulation | Cavitary Optic Disc Anomalies | Vitamin A Deficiency | Peutz-Jeghers Syndrome | Iron Overload | Macular Corneal Dystrophy | Glaucoma, Congenital | Lipid Metabolism Disorders | Blastomycosis | Gardner Syndrome | Portal Vein Thrombosis | Salla Disease | Stroke | Carotid Artery Disease | Neurodegeneration With Brain Iron Accumulation | Aromatic L-amino Acid Decarboxylase Deficiency | Imerslund-Grasbeck Syndrome | Anuria | Schamberg Disease | Filariasis | DNA Ligase IV Deficiency | Hoyeraal-Hreidarsson Syndrome | Muckle-Wells Syndrome | Orotic Aciduria | Adrenal Insufficiency | Bardet-Biedl Syndrome | Arthropathy | Glutaric Aciduria Type 3 | Leishmaniasis, Cutaneous | Agranulocytosis | Purpura, Thrombotic Thrombocytopenic | Kernicterus | Dermatofibrosarcoma | Angiosarcoma Of The Breast | Bainbridge-Ropers Syndrome | Hepatitis D | Bartter Syndrome | Spinocerebellar Ataxia Type 17 | Papilloma | Diabetes Insipidus | Lymphoma, AIDS-related | Major Depression | Pulmonary Veno-occlusive Disease | Neuropathy | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Paroxysmal Kinesigenic Dyskinesia | Light Chain Amyloidosis | Low Phospholipid Associated Cholelithiasis | Tinea | Urea Cycle Disorder | Cramp Fasciculation Syndrome | Cluster Headache | Anti-glomerular Basement Membrane Disease | Cenani-Lenz Syndactyly Syndrome | Craniolenticulosutural Dysplasia | Bloom Syndrome | Neurofibromatosis-Noonan Syndrome | Tinea Versicolor | Lymphedema | Sarcosinemia | Multiple Myeloma | Myoclonic Epilepsy With Ragged Red Fibers | Congenital Absence Of Vas Deferens | Lymphomatoid Granulomatosis | Hyperprolactinemia | Galactosialidosis | Takotsubo Cardiomyopathy | Perry Syndrome | LMNA-related Congenital Muscular Dystrophy | Congenital Myasthenic Syndrome | Aarskog-Scott Syndrome | Long QT Syndrome Type 2 | Pyruvate Kinase Deficiency | Aldosterone Deficiency | Varices | Spinocerebellar Ataxia Type 27 | Paracoccidioidomycosis | Familial Partial Lipodystrophy | Hypodontia | Sclerocornea | Encephalopathy, Glycine | Basal Ganglia Disease | Nephronophthisis | Meningococcal Infections | Diabetic Neuropathy | Greig Cephalopolysyndactyly Syndrome | Extramammary Paget's Disease | Pompe Disease | Aneurysm, Thoracic Aortic | Dysfibrinogenemia | Narcolepsy | Polyarteritis Nodosa | Congenital Torticollis | Motion Sickness | Porphyria | Chronic Enteropathy Associated With SLCO2A1 Gene | Sulfite Oxidase Deficiency | Hyperparathyroidism-jaw Tumor Syndrome | Early Infantile Epileptic Encephalopathy 28 | Dysplastic Nevus | Polymicrogyria | Hernia, Inguinal | Delayed Sleep Phase Syndrome | Tardive Dyskinesia | Martsolf Syndrome | Carbonic Anhydrase VA Deficiency | Schwannoma | Chronic Lymphocytic Leukemia | Vaginitis | X-linked Charcot-Marie-Tooth Disease | Epithelioid Hemangioma | Atrial Septal Defect | Cerebral Amyloid Angiopathy | Turner's Syndrome | Citrullinemia | Pyruvate Decarboxylase Deficiency | Sensorineural Hearing Loss | Giant Cell Glioblastoma | Phenylketonuria | Coronary Artery Disease | Retinal Dystrophy, Early-onset Severe | Mastitis | Omenn Syndrome | Iron Deficiency Anemia | Cancer, Kidney | Lactose Intolerance | Galactosemia | Ectodermal Dysplasia | Contact Dermatitis | Diabetic Macular Edema | Chronic Kidney Disease | Campomelic Dysplasia | Coma | Glutaric Aciduria Type 1 | Poretti-Boltshauser Syndrome | Trimethylaminuria | Congenital Hypofibrinogenemia | Charcot-Marie-Tooth Disease Type 3 | Hereditary Xerocytosis | Aicardi-Goutieres Syndrome | Gynecomastia | Vitelliform Macular Dystrophy | Wiskott-Aldrich Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Pancreatitis, Chronic | Combined Pituitary Hormone Deficiency | Hepatic Steatosis | Echinococcosis | Bronchiolitis | Asthma, Nocturnal | Episodic Ataxia Type 2 | Microcephaly, Seizures, And Developmental Delay | Spinocerebellar Ataxia Type 14 | Guillain-Barre Syndrome | Parkinson Disease 6, Autosomal Recessive Early-onset | Rhabdomyosarcoma, Embryonal | Oligoasthenoteratozoospermia | Dermatitis Herpetiformis | Pseudohermaphroditism | Oculocutaneous Albinism Type 2 | Stiff-man Syndrome | Schizencephaly | Focal Dermal Hypoplasia | Oral Lichen Planus | Dent Disease | Niemann-Pick Disease, Type A | Polycystic Kidney, Autosomal Dominant | DEND Syndrome | Prolymphocytic Leukemia | Glomerulonephritis, Membranoproliferative | Exostoses | Hyperinsulinemic Hypoglycemia | Leprosy | Combined Malonic And Methylmalonic Acidemia | Thyroiditis, Autoimmune | Klinefelter Syndrome | Renal Hypouricemia | Enterocolitis, Necrotizing | Gnathodiaphyseal Dysplasia | Jaundice, Obstructive | Pemphigoid | Brachial Plexus Neuropathy | Osteoporosis-pseudoglioma Syndrome | Adenoma, Villous | Familial Hypertrophic Cardiomyopathy | Herpes Simplex Dermatitis | Gingivitis | 3-methylglutaconic Aciduria Type IV | Meleda Disease | Trichorhinophalangeal Syndrome | Optic Nerve Diseases | Familial Retinal Arterial Macroaneurysm | Hypermethioninemia | Delirium | Hereditary Hemorrhagic Telangiectasia | Metabolic Diseases | Hyperkeratosis | Goiter, Nodular | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Phosphoglycerate Dehydrogenase Deficiency | Spinocerebellar Ataxia Type 42 | Glaucomatocyclitic Crisis | B-cell Prolymphocytic Leukemia | Hypersensitivity | Pyruvate Dehydrogenase Deficiency | Gliosarcoma | Arrhythmogenic Right Ventricular Cardiomyopathy | Diabetes Type 1 | Acute Myeloid Leukemia | Hereditary Coproporphyria | Melanocytic Nevus | Cutaneous Mastocytosis | Autoimmune Polyendocrinopathy Syndrome Type I | Osteogenesis Imperfecta | Irritable Bowel Syndrome | Rolandic Epilepsy | Noonan Syndrome-like Disorder With Loose Anagen Hair | Currarino Syndrome | Pneumoconiosis | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Hypogammaglobulinemia | Lathosterolosis | Congenital Disorders Of Glycosylation | Angioedema, Acquired | Esophageal Adenocarcinoma | Myocarditis | Incontinentia Pigmenti | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Photosensitivity | Neurofibrosarcoma | Klippel-Feil Syndrome | Methemoglobinemia | Fibrodysplasia Ossificans Progressiva | Congenital Sodium Diarrhea | Uremia | Stickler Syndrome | Episodic Ataxia Type 1 | Limb Girdle Muscular Dystrophy | Infertility | Melanoma | Charcot-Marie-Tooth Disease Type 2E | Meconium Ileus | Leukoplakia | Waldenstrom Macroglobulinemia | Transcobalamin Deficiency | Anti-NMDA Receptor Encephalitis | Alopecia Areata | Ependymoma | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Subacute Sclerosing Panencephalitis | Central Core Disease | Tyrosinemia Type 1 | Schwartz-Jampel-Aberfeld Syndrome | Primary Ovarian Insufficiency | Senior-Loken Syndrome | Myositis, Focal | Neuromuscular Disorders | Thrombosis | Alpha-1 Antitrypsin Deficiency | Amenorrhea | Chondrodysplasia Punctata 1, X-linked Recessive | Tylosis With Esophageal Cancer | Spinocerebellar Ataxia Type 2 | Peeling Skin Syndrome, Acral Type | Dengue Shock Syndrome | Medulloblastoma | Bursitis | Becker Muscular Dystrophy | Carney Triad | Fibrosarcoma | Fibronectin Glomerulopathy | Influenza | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Purpura | Aphasia | Renal Hypomagnesemia 3 | Leri-Weill Dyschondrosteosis | Atrioventricular Septal Defect | Mabry Syndrome | VACTERL/VATER Association | Costello Syndrome | Lymphoma, B-cell | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Sandhoff Disease | Congenital Heart Block | Pheochromocytoma | Mitochondrial Disease | Niemann-Pick Disease, Type C | Gilbert Syndrome | Heart Septal Defects | Hypoplastic Left Heart Syndrome | Xeroderma Pigmentosum Variant Type | Chronic Idiopathic Myelofibrosis | Genitopatellar Syndrome