Gyrate Atrophy Of The Choroid And Retina

About the Disease
Gyrate Atrophy of Choroid and Retina, also known as gyrate atrophy, is related to macular retinal edema and macular dystrophy, dominant cystoid. An important gene associated with Gyrate Atrophy of Choroid and Retina is OAT (Ornithine Aminotransferase), and among its related pathways/superpathways are Regulation of expression of SLITs and ROBOs and Visual phototransduction. The drugs Ornithine and Pyridoxine have been mentioned in the context of this disorder. Affiliated tissues include retina, eye and spinal cord, and related phenotypes are progressive visual loss and myopia

Common Targets
OAT | RPE65

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