Thyroid Dysgenesis

About the Disease
Hypothyroidism, Congenital, Nongoitrous, 2, also known as thyroid dysgenesis, is related to hypothyroidism, thyroidal or athyroidal, with spiky hair and cleft palate and graves ophthalmopathy. An important gene associated with Hypothyroidism, Congenital, Nongoitrous, 2 is PAX8 (Paired Box 8), and among its related pathways/superpathways is Thyroxine (thyroid hormone) production. The drugs Dexamethasone acetate and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include thyroid, pituitary and tongue, and related phenotypes are constipation and hypothyroidism

Common Targets
DUOXA2 | GLIS3 | DUOX2 | TUBB1

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