Osteogenesis Imperfecta Type II

About the Disease
Osteogenesis Imperfecta, Type Ii, also known as vrolik type of osteogenesis imperfecta, is related to osteogenesis imperfecta, type vii and osteogenesis imperfecta, type v. An important gene associated with Osteogenesis Imperfecta, Type Ii is COL1A2 (Collagen Type I Alpha 2 Chain), and among its related pathways/superpathways are Phospholipase-C Pathway and Collagen chain trimerization. Affiliated tissues include bone, eye and skin, and related phenotypes are thin ribs and thoracic hypoplasia

Common Targets
COL1A1 | COL1A2

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