Disease

Neutropenia

About the Disease
Neutropenia, also known as leukopenia, is related to poikiloderma with neutropenia and cyclic neutropenia. An important gene associated with Neutropenia is ELANE (Elastase, Neutrophil Expressed), and among its related pathways/superpathways are Hematopoietic Stem Cells and Lineage-specific Markers and Other interleukin signaling. The drugs Ceftazidime and Lenograstim have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, breast and bone marrow, and related phenotypes are no effect and no effect

Common Targets
FFAR1 | BAALC | NAT2 | CYP1A1 | XDH | GSTM3 | MAP2K7 | G7157 | TLR2 | G7015 | GSK3B | CDYL2 | GSTT1 | RRM1 | PMS2 | SLC28A1 | MMP2 | ATIC | PPARD | MROH2A | CDA | RAD52 | TPMT | ABCC5 | MUTYH | MOCOS | MTRR | XRCC2 | GAS5 | ABCC2 | SLC7A5 | RNF115 | HAX1 | PHRF1 | CSF3R | CRIM1 | SLCO5A1 | GSTA5 | CES2 | PSMD3 | CCN2 | ABCB4 | GSTM5 | SLC7A7 | BTNL2 | TNFSF13B | G4193 | KCNN4 | CASC8 | GSTA1 | SLC13A1 | IQCM | GSAP | TLR9 | ERCC2 | UGT1A7 | GM-CSF Receptor (GM-CSF-R) | ABCG1 | TET2 | G6PC3 | FCGR3A | GSTP1 | DCK | SENP7 | GADD45B | CES1 | SYT16 | ATP7A | CHD2 | ADORA3 | G7099 | SLC19A1 | TMEM63A | SLC22A6 | Interleukin-12 (IL-12) | SULT2A1 | XRCC3 | PDZRN3 | REV1 | KAT6A | IL15 | SLC15A1 | CYP3A5 | MORC4 | NUDT15 | ADH1B | GSDMA | G581 | GATA2 | GSTA2 | IMPDH1 | DAPK1 | CPAMD8 | SLC22A2 | SETBP1 | UGT1A6 | MAPK9 | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | LOC105373874 | CTNNB1 | G672 | GSTM1 | SULT1E1 | ADGRL2 | REV3L | GADD45A | ACTN1 | C3AR1 | AQP8 | UGT2B7 | TUBB1 | UGT1A9 | SLC29A3 | PTPN11 | HLA-DQB1 | ABL1 | CASC21 | SLC4A7 | EBF2 | CYP4F11 | KLC3 | PON1 | LGR6 | CXCR2 | IMPDH2 | IL-3 receptor | CYP2C9 | GPR84 | SLC22A16 | GADD45G | HNF1A | TYMS | UGT1A1 | USB1 | PKD1L1 | MAOB | EPOR | SLCO1B1 | FCGR2A | CYP39A1 | MPL | UGT2B15 | IGFBP-AS1 | FGFR2 | DLX2-DT | XRCC1 | G5243 | SEMA3C | G238 | HUWE1 | C5AR1 | ZNF365 | FMO6P | ERCC4 | ITPA | NME1 | DHFR | ALB | CHEK2 | ABCC1 | CCDC170 | RUNX1 | TCIRG1 | SLC5A11 | SLC22A4 | JAGN1 | HIF1A | NQO1 | MTHFR | HK2 | CYP2B6 | G7124 | CHST9 | G4780 | PPARG | VPS45 | ELANE | ARHGAP26 | POLR2A | FPGS | CYP4F2 | EPHX1 | ABCC4 | HLA-B | Phosphodiesterase IV (PDE4) (nonspecified subtype) | TNFRSF1A | MSH6 | CSF2RA | CYP1B1 | CES1P1 | MPO | SLCO3A1 | G3569 | DPYD | ATP2B3 | UMPS | LINC02778 | SLC29A1 | FMO3 | Tubulin | BRCA2 | MYO1E | SLCO1B3 | SLCO1A2 | GGH | ALDOB | OR4D6 | KDR | ERCC5 | LIG3 | CYP2C19 | ABCC10 | MRTFA | Interleukin 23 complex (IL-23) | SLC31A1 | ZMIZ1 | CYBA | IL1B | MDM4 | MAT1A | CTDP1 | TERC | ERCC1 | FANCC | FAP | G9429 | ITPR1 | SLC51A | ALG10 | C5 | INPP5D | GALNT14 | HSPA2 | G7852 | XPC | G5599 | CSF3 | AGBL4 | MAP2K4 | FCGR2B | COL7A1 | RECQL5 | ALDH2 | HELB | NT5C2 | ADAM29 | G1432 | G1026 | TUBB | CYP2D6 | BABAM1 | ADK | MAP3K4 | CEBPE | STAT6 | SULT1A1 | ATXN7 | G2064 | FLT3 | BIVM-ERCC5 | AKAP9 | OR51S1 | DCLRE1B | SLC28A3

疾病靶点研报
Neutropenia

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