Dowling-Meara Type Epidermolysis Bullosa Simplex

About the Disease
Epidermolysis Bullosa Simplex 1a, Generalized Severe, also known as epidermolysis bullosa simplex, dowling-meara type, is related to epidermolysis bullosa simplex 5a, ogna type and epidermolysis bullosa simplex 1b, generalized intermediate, and has symptoms including nail shedding An important gene associated with Epidermolysis Bullosa Simplex 1a, Generalized Severe is KRT14 (Keratin 14), and among its related pathways/superpathways are Nervous system development and Cell junction organization. Affiliated tissues include skin and tongue, and related phenotypes are palmoplantar keratoderma and erythema

Common Targets
KRT5

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