Disease

Waldenstrom Macroglobulinemia

About the Disease
Lymphoplasmacytic Lymphoma, also known as waldenstr?m macroglobulinaemia without mention of remission, is related to macroglobulinemia and waldenstroem's macroglobulinemia. An important gene associated with Lymphoplasmacytic Lymphoma is PAX5 (Paired Box 5), and among its related pathways/superpathways are Innate Immune System and Disease. The drugs Thalidomide and Chlorambucil have been mentioned in the context of this disorder. Affiliated tissues include b cells, bone marrow and t cells, and related phenotypes are homeostasis/metabolism and cellular

Common Targets
RBFOX1 | G7124 | PSMB5 | G3630 | MED23 | mTOR complex 1 | BCR | LCK | G598 | PCDHA5 | MUC16 | MAP2 | HCLS1 | NR1H3 | Ephrin Receptor (nonspecified subtype) | BMX | SYK | CLSTN2 | LOC102724428 | MIR155 | TRRAP | G836 | TNFSF13B | FAM219A | CD38 | G7157 | NEUROG1 | MICALL1 | NF-kappaB (NFkB) | PDE5A | IRAK4 | PDGFRA | TLR9 | MS4A1 | ADA | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | KIT | Adenosine deaminase (nonspecified subtype) | HAS1 | DDR1 | mTOR complex 2 | MAP4K1 | Proteasome Complex | EPHB6 | BLK | Histone deacetylase (nonspecified subtype) | MAP3K7 | CRBN | PRKCB | CD70 | LARGE1 | SIK2 | LYN | ZMAT5 | Janus Kinase (nonspecified subtype) | FHL2 | G596 | FRK | ABL1 | DOCK2 | TRIM31 | NOTCH2 | MYBBP1A | BRWD1 | ARID1A | TNFRSF17 | FYN | SIK1 | CD19 | CHST4 | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | TLR7 | AMP-activated protein kinase (AMPK) | PDGFRB | CSF1R | BTK | G2475 | ELANE | G6714 | PIK3CA | EXOC2 | G5243 | RAG2 | TLR8 | LAPTM5 | DNA-Dependent Protein Kinase (DNA-PK) | YES1 | HCK | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | CSK | PIK3CD | MYD88 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | FGR | CSNK1E | DDR2 | G9429 | FKBP1A | G7852

疾病靶点研报
Waldenstrom Macroglobulinemia

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