X-linked Chronic Granulomatous Disease, CGD

About the Disease
Granulomatous Disease, Chronic, X-Linked, also known as chronic granulomatous disease, x-linked, is related to granulomatous disease, chronic, autosomal recessive, 4 and granulomatous disease, chronic, autosomal recessive, 3. An important gene associated with Granulomatous Disease, Chronic, X-Linked is CYBB (Cytochrome B-245 Beta Chain), and among its related pathways/superpathways are Signal Transduction and Class I MHC mediated antigen processing and presentation. The drugs Plerixafor and Ibuprofen have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and bone marrow, and related phenotypes are hepatomegaly and fever

Common Targets
NOD2 | CYBB

Note: If you'd like to get a target analysis report for X-linked Chronic Granulomatous Disease, CGD, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of X-linked Chronic Granulomatous Disease, CGD at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Albinism | Alpha-thalassemia Myelodysplasia Syndrome | Enlarged Vestibular Aqueduct | Enterocolitis, Necrotizing | Schizencephaly | Choroiditis | Sturge-Weber Syndrome | Congenital Diaphragmatic Hernia | Trismus-pseudocamptodactyly Syndrome | Loeys-Dietz Syndrome | Juvenile Xanthogranuloma | Biotinidase Deficiency | Familial Episodic Pain Syndrome | Meier-Gorlin Syndrome | Peutz-Jeghers Syndrome | Sweet Syndrome | Hyperbilirubinemia | Pierson Syndrome | Non-Langerhans Cell Histiocytosis | Spinocerebellar Ataxia Type 8 | Placenta Previa | Optic Neuritis | Gitelman Syndrome | Feingold Syndrome | Actinomycetoma | Angiodysplasia | Chronic Idiopathic Myelofibrosis | Analgesia | Mevalonate Kinase Deficiency | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Autoimmune Autonomic Ganglionopathy | Retinal Dystrophy | Chitayat Syndrome | Allergic Contact Dermatitis | Urticaria | T-cell Chronic Lymphocytic Leukemia | Meningococcal Meningitis | Hidradenitis Suppurativa | Bainbridge-Ropers Syndrome | Methylmalonic Acidemia | Tenosynovial Giant Cell Tumor | Hyperprolactinemia | Thrombocythemia, Essential | Anterior Segment Dysgenesis | Basal Cell Nevus Syndrome | Shock, Cardiogenic | Meningioma | Amelanotic Melanoma | Glycogen Storage Disease Type 1 | Lung Diseases | Hypokalemic Periodic Paralysis | GAPO Syndrome | Crohn's Disease | Pitt-Hopkins Syndrome | Postpoliomyelitis Syndrome | Klinefelter Syndrome | Primary Cutaneous Amyloidosis | Hairy Cell Leukemia | Persistent Fetal Circulation | Coenzyme Q10 Deficiency | Ganglioneuroma | Pneumonia, Mycoplasma | DiGeorge Syndrome | Oculopharyngeal Muscular Dystrophy | Histoplasmosis | Hypercholesterolemia | Carcinoma, Transitional Cell | Congenital Hypofibrinogenemia | Cantu Syndrome | Multicystic Renal Dysplasia | Atrioventricular Septal Defect | Otitis Media | Fibromyalgia | Sandhoff Disease | Blastomycosis | Diabetes Type 2 | Multiple Sclerosis | Danon Disease | Short-chain Acyl-CoA Dehydrogenase Deficiency | Blepharo-cheilo-odontic Syndrome | Angioedema | Panic Disorder | Congenital Absence Of Vas Deferens | Parvovirus B19 Infection | Gyrate Atrophy Of The Choroid And Retina | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Prune Belly Syndrome | Encephalopathy, Hepatic | Leukocyte Adhesion Deficiency | Scapuloperoneal Spinal Muscular Atrophy | Gastritis | Histiocytic Sarcoma | Zygomycosis | Renal Hypouricemia | 5-oxoprolinase Deficiency | Cysticercosis | Vitamin K Deficiency | Knobloch Syndrome | Gastroenteritis, Eosinophilic | Trachoma | Epithelial-myoepithelial Carcinoma | Spinocerebellar Ataxia Type 6 | Nephrotic Syndrome Type 1 | Obesity | PHARC Syndrome | Myocardial Infarction | Schaaf-Yang Syndrome | Encephalitis | Agammaglobulinemia | Alazami Syndrome | Arthropathy | Atelosteogenesis Type 1 | Beta-Propeller Protein-associated Neurodegeneration | Periodontitis | 3-methylglutaconic Aciduria | Hydrocephalus | Megaloblastic Anemia | Turner's Syndrome | Retinal Diseases | Costello Syndrome | Keratosis, Actinic | Anorectal Fistula | Focal Segmental Glomerulosclerosis | Chronic Neutrophilic Leukemia | Frontotemporal Dementia | Prolactinoma | Photosensitivity | Basal Ganglia Disease | Specific Granule Deficiency | Pilomatrix Carcinoma | Congenital Poikiloderma | Hepatitis D | Colitis, Microscopic | Glomerulonephritis, Membranoproliferative | Hyperinsulinemia | Mitochondrial DNA Depletion Syndrome 13 | Sialidosis Type I | CEDNIK Syndrome | Primary Hyperoxaluria | Acute Anterior Uveitis | Polymyositis | Malnutrition | Bruck Syndrome | Borderline Personality Disorder | Porokeratosis | Kawasaki Disease | Iron Deficiency Anemia | Dermatofibrosarcoma | Astrocytoma | Zimmermann-Laband Syndrome | Alexander Disease | Central Retinal Artery Occlusion | Keratosis | Sialoadenitis | Epidermolysis Bullosa | Genee-Wiedemann Syndrome | Osteitis | Systemic Mastocytosis | Aspartylglycosaminuria | CHOPS Syndrome | Keratoacanthoma | Kaposiform Hemangioendothelioma | Argininosuccinic Aciduria | Hemorrhoids | Stuttering | Gastroschisis | Fragile X Syndrome | Nance-Horan Syndrome | Alopecia | Familial Retinal Arterial Macroaneurysm | Spinal Muscular Atrophy Type 3 | Chronic Thromboembolic Pulmonary Hypertension | Perry Syndrome | Marshall-Smith Syndrome | Acrodermatitis Enteropathica | Inflammatory Linear Verrucous Epidermal Nevus | Oculodentodigital Dysplasia | Esophageal Motility Disorders | Pulmonary Vein Stenosis | Wolfram Syndrome 2 | Leukoencephalopathy, Progressive Multifocal | Benign Recurrent Intrahepatic Cholestasis 1 | Apparent Mineralocorticoid Excess Syndrome | Erdheim-Chester Disease | Galactosialidosis | Anxiety Disorders | Distal Myopathy 2 | Astigmatism | Meniere's Disease | Cancer, Prostate | Pseudohermaphroditism | Ileitis | Fanconi Syndrome | Aromatic L-amino Acid Decarboxylase Deficiency | Congenital Dyserythropoietic Anemia Type 4 | Metabolic Diseases | Echinococcosis | Intestinal Obstruction | Ellis-Van Creveld Syndrome | Otitis Externa | Cardiomyopathy, Hypertrophic | Schistosomiasis | Lymphangiomatosis | Acrocallosal Syndrome | Goiter | Agoraphobia | Genitopatellar Syndrome | Cryoglobulinemia | Rosacea | Cerebellofaciodental Syndrome | Pericarditis | Autoimmune Disease | Trichomegaly | Juvenile Polyposis | Osmotic Demyelination Syndrome | Gigantism | Contact Dermatitis | Sjogren Syndrome | Dowling-Degos Disease | Multiple Sclerosis, Relapsing-remitting | Primary Erythromelalgia | Cenani-Lenz Syndactyly Syndrome | Nestor-Guillermo Progeria Syndrome | Tremor | Glycogen Storage Disease Type 9 | Onchocerciasis | Pyloric Stenosis, Infantile Hypertrophic | Peripheral Neuropathy | Multifocal Motor Neuropathy | Atrial Septal Defect | Martsolf Syndrome | Aldosterone Synthase Deficiency | Hepatic Steatosis | Osteogenesis Imperfecta Type II | Acromesomelic Dysplasia | Bladder Exstrophy | Porphyria, Variegate | Erythema Nodosum | Hepatitis, Alcoholic | Mucolipidosis Type III | Behcet's Disease | Tatton-Brown-Rahman Syndrome | Muscle Wasting | Idiopathic Pulmonary Fibrosis | Hypersomnia | Progressive Familial Intrahepatic Cholestasis | GATA2 Deficiency | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Pterygium | Sarcoidosis | Bronchiolitis | Chronic Granulomatous Disease, X-linked | Hemosiderosis | Chronic Lymphocytic Leukemia | Brachydactyly | Tyrosinemia Type 1 | Familial Pheochromocytoma-paraganglioma | Fibrosis | Leiomyoma | Xeroderma Pigmentosum | Bartter Syndrome | Hyperoxaluria | Microvillus Inclusion Disease | Sleep Apnea | Binge Eating Disorder | Adrenoleukodystrophy, X-linked | Aplasia Cutis Congenita | Lymphoma, Follicular | DOCK8 Immunodeficiency Syndrome | Guanidinoacetate Methyltransferase Deficiency | Asthma | Hypothyroidism | Adrenomyeloneuropathy | Ophthalmia, Sympathetic | Hypertension, Renovascular | Phosphoglycerate Dehydrogenase Deficiency | Craniosynostosis | Congenital Aniridia | Hyperphenylalaninemia | Infantile Refsum Disease | HANAC Syndrome | Heterotopic Ossification | Cystinuria | Polycystic Ovary Syndrome | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | GM2-gangliosidosis AB Variant | Irritable Bowel Syndrome | Sponastrime Dysplasia | Dysplastic Nevus | Filariasis | Spinocerebellar Ataxia Type 15 | Blue Rubber Bleb Nevus Syndrome | Glanzmann Thrombasthenia | MELAS Syndrome | Leri Pleonosteosis | Pulmonary Sclerosing Hemangioma | Epidermolytic Palmoplantar Keratoderma | Hepatopulmonary Syndrome | Pemphigus Foliaceus | Extramammary Paget's Disease | Infantile Liver Failure Syndrome 1 | Hereditary Multiple Exostoses | Intestinal Tuberculosis | Diabetes Type 1 | Charcot-Marie-Tooth Disease Type 2T | Chondromyxoid Fibroma | Chordoid Glioma | Osteochondroma | Diarrhea | Pityriasis Rubra Pilaris | Chronic Periodontitis | Pompe Disease | Cerebral Amyloid Angiopathy | N-acetylglutamate Synthase Deficiency | Cat Eye Syndrome | Canavan Disease | Crouzon Syndrome With Acanthosis Nigricans | Spinocerebellar Ataxia Type 38 | Autoimmune Polyendocrinopathy Syndrome Type I | Glycogen Storage Disease Type 3 | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Coffin-Lowry Syndrome | Glycogen Storage Disease Type 1a | Thrombasthenia | Ornithine Transcarbamylase Deficiency | Chanarin-Dorfman Syndrome | Glycogen Storage Disease Type 5 | Erectile Dysfunction | Osteoarthritis | Hennekam Lymphangiectasia-lymphedema Syndrome | Conn Syndrome | Spinocerebellar Ataxia Type 23 | Hypotonia-cystinuria Syndrome | Exocrine Pancreatic Insufficiency | Congenital Lipoid Adrenal Hyperplasia | Neuroectodermal Tumors, Primitive | Meconium Ileus | Fukuyama Congenital Muscular Dystrophy | Fibrodysplasia Ossificans Progressiva | Myoclonus | Macular Corneal Dystrophy | Reticular Dysgenesis | Spondylolisthesis | Thrombotic Microangiopathy | Triple A Syndrome | Raine Syndrome | Hypertrophy | Netherton Syndrome | Tetraplegia | Distal Spinal Muscular Atrophy | Nicotine Addiction | Heavy Chain Disease | Papilledema | Hemorrhagic Disorders | Nephrotic Syndrome | Currarino Syndrome | Lymphangioma | Creatine Deficiency Syndrome | 3-methylglutaconic Aciduria Type IV | Primary Progressive Aphasia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | GNE Myopathy | Scabies | Amish Infantile Epilepsy Syndrome | Influenza | Malignant Peripheral Nerve Sheath Tumor | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Melanoma, Uveal | Exotropia | Hyperuricemia | Robinow Syndrome | TARP Syndrome | Liebenberg Syndrome | Neurodevelopmental Disorders | Trichorhinophalangeal Syndrome | Cole-Carpenter Syndrome | Fuchs Dystrophy | Niemann-Pick Disease | Hyperlipidemia, Familial Combined | Cold-induced Sweating Syndrome | Rheumatic Heart Disease | Spinocerebellar Ataxia Type 17 | Neural Tube Defect | Charcot-Marie-Tooth Disease Axonal Type 2N | Lymphedema | Empyema | Progressive Encephalopathy-optic Atrophy Syndrome | Hepatitis, Chronic | Autosomal Recessive Spastic Paraplegia Type 35 | Lattice Corneal Dystrophy | Raynaud Phenomenon | Low Phospholipid Associated Cholelithiasis | Adenoma, Pleomorphic | Atelosteogenesis Type 2 | Porphyria Cutanea Tarda | Posterior Polar Cataract | Thromboembolism | Isobutyryl-CoA Dehydrogenase Deficiency | Keratoconjunctivitis | Lymphoma, AIDS-related