Kawasaki Disease

About the Disease
Kawasaki Disease, also known as mucocutaneous lymph node syndrome, is related to exanthem and conjunctivitis, and has symptoms including fever, congestion of ocular conjunctivae and reddening of lips. An important gene associated with Kawasaki Disease is THRIL (TNF And HNRNPL Related Immunoregulatory Long Non-Coding RNA), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Immunoglobulin G and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include body, lymph node and heart, and related phenotypes are proteinuria and cheilitis

Common Targets
MMP3 | IZUMO1 | COLEC11 | HAMP | VDR | TLR10 | G3569 | HMGCR | TRAF3IP2-AS1 | G4318 | CREM | G3630 | DERL3 | TNFSF14 | PSMA3 | SEMA6A | MMP17 | ORAI1 | MMP11 | HLA-A | G7124 | CDYL2 | MMP19 | CDH12 | PPP3R2 | NOS3 | NAGPA | IL1B | LOC105379664 | MMP21 | IL10 | IL-1 Receptor (nonspecified subtype) | NPSR1 | MMP12 | PPP3CC | DPP4 | MMP24 | CD14 | MMP25 | BTNL2 | TLR2 | G7422 | CD40 | PPID | GRM6 | COQ8B | ADAM17 | SAMD9L | TBX21 | SMAD5 | G836 | MMP2 | MSH5 | NFATC2 | CTLA4 | LOC101927995 | G7157 | IL17REL | HLA-DOB | MICB | LY75 | TLR9 | PDGFRA | BICC1 | PSMA6 | IL1A | CXCL12 | REV3L | MMP7 | GZMB | CLEC4C | MMP26 | PECAM1 | P2RY12 | ADRB2 | FASLG | FGB | Trypsin (nonspecified subtype) | EBF2 | MBL2 | Serine protease (nonspecified subtype) | MMP13 | TTLL8 | CCR5 | TPD52 | BLK | TGFB2 | MIR146A | SARNP | ANKRD55 | USF2 | IL4 | G7099 | PDE2A | LOC107984146 | TGFB1 | HLA-DQB1 | NLRP14 | FCGR2A | NMNAT2 | G5133 | HLA-DPB1 | AGER | PPP3CB | CCL17 | FCN1 | FBXL19 | PPP3R1 | HLA-C | SMAD3 | C1QTNF1 | LINC00707 | RASIP1 | IL13 | IL5RA | HSPA1A | CNTN1 | IL16 | C5AR1 | MIA | GPR6 | G3146 | MMP8 | SULT1A2 | RAB31 | FUT1 | CXCL10 | IL12A-AS1 | MMP28 | PLA2G7 | TPRXL | SETD1A | TLR7 | CRP | IL18 | HLA-DRB1 | TGFBR2 | STX1B | MMP1 | EPB41L3 | TLR6 | MMP27 | ABCC4 | IFITM3 | MMP14 | TAP1 | ELANE | MICA | MPO | ITPKC | HSPA1L | IL1RN | STX4 | SLC11A1 | PEX6 | TRAF3IP2 | FCER1A | HLA-B | RORC | OPCML | TLR1 | FCGR3B | MIR3142HG | TLR3 | TAP2 | THBD | Protein Phosphatase 2B | TLR8 | MMP20 | SELE | MMP10 | PPIA | SPP1 | MTHFR | LINC02571 | ADAM33 | Interleukin 17 (nonspecified subtype) | CYFIP2 | NR3C1 | APBB2 | ACTMAP | C5 | PIK3CD | CD40LG | HLA-DQA1 | ELF5 | FCGR2B | MMP16 | CD209 | TLR5 | BAG6 | MMP23B | MPPED1 | MAMSTR | PTGS1 | AGT | LOC101928762

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