Fabry's Disease

About the Disease
Fabry Disease, also known as alpha-galactosidase a deficiency, is related to kanzaki disease and schindler disease, and has symptoms including abdominal pain, angina pectoris and muscular fasciculation. An important gene associated with Fabry Disease is GLA (Galactosidase Alpha), and among its related pathways/superpathways are Innate Immune System and Senescence and autophagy in cancer. The drugs Coal tar and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include skin, heart and eye, and related phenotypes are corneal opacity and arthritis

Common Targets
RAB5C | HMOX1 | GBA1 | AGT | UGCG | BRD2 | ADH4 | LOC100507053 | Chaperone (nonspecified subtype) | BRD4 | SLC5A4 | Ceramidase (nonspecified subtype) | RPL36A-HNRNPH2 | MAN2A1 | COL4A3 | APOA1 | BRD3 | GAA | NPC1 | AGTR1 | UGT1A1 | GLA

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