WAGR Syndrome

About the Disease
Wilms Tumor, Aniridia, Genitourinary Anomalies, and Mental Retardation Syndrome, also known as wagr syndrome, is related to aniridia 2 and gillespie syndrome, and has symptoms including genitourinary signs and symptoms An important gene associated with Wilms Tumor, Aniridia, Genitourinary Anomalies, and Mental Retardation Syndrome is WT1 (WT1 Transcription Factor), and among its related pathways/superpathways are Mesodermal commitment pathway and BMP signaling in eyelid development. Affiliated tissues include Kidney, eye and testes, and related phenotypes are aplasia/hypoplasia of the iris and aniridia

Common Targets
PAX6 | LDHD

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