Bullous Pemphigoid

About the Disease
Bullous Pemphigoid, also known as senile dermatitis herpetiformis, is related to epidermolysis bullosa acquisita and dermatitis herpetiformis. An important gene associated with Bullous Pemphigoid is HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ Beta 1), and among its related pathways/superpathways are Signal Transduction and ERK Signaling. The drugs Hydrocortisone and Hydrocortisone succinate have been mentioned in the context of this disorder. Affiliated tissues include skin, salivary gland and bone, and related phenotypes are diabetes mellitus and autoimmunity

Common Targets
CYP2D6 | G5243 | C1S | IL17RA | HLA-A | FCGRT | C-X-C Chemokine Receptor CXCR1/CXCR2 (IL-8 Receptor) (nonspecified subtype) | HLA-G | CXCR1 | IL-4 receptor | G7124 | GZMB | CCL11 | IL5 | COL17A1 | CXCR2 | Immunoglobulin E (IgE) | IL4 | HLA-DPB1 | HLA-DQB1 | IL5RA | C3 | IL13 | C5AR1 | ATP8 | HLA-DRB1 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | ELANE | HLA-B | CCR3 | HLA-DQA1 | C5

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