Disease

Interstitial Lung Diseases

About the Disease
Interstitial Lung Disease, also known as ild, is related to interstitial pneumonitis, desquamative, familial and rheumatoid arthritis interstitial lung disease, and has symptoms including shortness of breath, coughing and hemoptysis. An important gene associated with Interstitial Lung Disease is INPP5E (Inositol Polyphosphate-5-Phosphatase E), and among its related pathways/superpathways are Innate Immune System and Metabolism of proteins. The drugs Prednisone and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include lung, bone marrow and skeletal muscle, and related phenotypes are homeostasis/metabolism and neoplasm

Common Targets
P2RX1 | HLA-A | LPAR1 | ALOX5AP | GLIS3 | TGFBR1 | D21S2088E | G3480 | FARSB | XDH | G7422 | LINC01239 | NKX2-1 | G7015 | MMP12 | Tyrosine Kinase (nonspecified subtype) | IVD | AQP4 | CTLA4 | NF-kappaB (NFkB) | SFTPA1 | CCN2 | HER (erbB) (nonspecified subtype) | SERPINE1 | SSH2 | NOX4 | CHIT1 | PDGFRA | PDE5A | CD86 | TOLLIP | KIT | ITGA3 | FARSA | Interleukin-12 (IL-12) | IFNG | DSP | SFTPC | DDR1 | STAT4 | NOX3 | LIPC | TGFB1 | Transforming growth factor beta (nonspecified subtype) | RTEL1 | HLA-DQB1 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | ABL1 | CD80 | PON1 | NADPH Oxidase Complex | Nitric oxide synthase (NOS) (nonspecified subtype) | IL6R | LOXL2 | HLA-DPB1 | MIR3667HG | Integrin alphavbeta6 receptor | SFTPA2 | SFTPD | HLA-C | LINC01276 | AGTR2 | G6774 | PDGFRB | Cytochrome P450 Enzymes (nonspecified subtype) | CSF1R | MARS1 | NADPH Oxidase (nonspecified subtype) | HLA-DRB1 | CCL18 | MEP1A | NOX1 | GRIN2B | MEP1B | LIPE | DAGLA | ELANE | G5243 | G4780 | SLC25A48 | CCSER1 | PDE4D | PORCN | LTC4S | HLA-B | TGFB3 | GRN | ABCA3 | Integrin alphavbeta8 Receptor | CMA1 | RPA3 | TSHZ2 | FGFR3 | LIPG | G7124 | TYK2 | TNFRSF13B | HABP4 | ENPP2 | SPP1 | G3569 | CACNA1H | Integrin alphavbeta3 (vitronectin) receptor | KDR | ZC3H12A | PDE4B | UMAD1 | HLA-DQA1 | BRD4 | G9429 | FLT4 | FGFR1 | FLT1 | TSNARE1 | PREP | SNAI3-AS1 | IKBKB | VDR | ZNF664-RFLNA | VAMP1 | PARN | ALDH2 | BCR | G1950 | Folate Receptor (nonspecified subtype)

疾病靶点研报
Interstitial Lung Diseases

Note: If you'd like to get a target analysis report for Interstitial Lung Diseases, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Interstitial Lung Diseases at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Connective Tissue Disorders | McCune-Albright Syndrome | Chondroma | Chordoma | Periodic Limb Movement Disorder | Rotor Syndrome | Keratoconus | Epithelioid Hemangioma | Hypokalemic Periodic Paralysis | Stroke, Hemorrhagic | Anti-glomerular Basement Membrane Disease | Woodhouse-Sakati Syndrome | Retinal Dystrophy | Anodontia | 3C Syndrome | Protein S Deficiency | Nephrocalcinosis | CHOPS Syndrome | Sengers Syndrome | Early Infantile Epileptic Encephalopathy 1 | Chylomicron Retention Disease | Hyperprolactinemia | Chromosome 17q21.31 Deletion Syndrome | Transient Bullous Dermolysis Of The Newborn | Congenital Myopathy | Pancytopenia | Hyperammonemia | Cenani-Lenz Syndactyly Syndrome | Polycythemia Vera | Primary Erythromelalgia | Progressive External Ophthalmoplegia | WAGR Syndrome | Osteomyelitis | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Blastoma, Pleuropulmonary | Combined Malonic And Methylmalonic Acidemia | Peters-plus Syndrome | Glomerulonephritis, Membranous | Presbyopia | Cold-induced Sweating Syndrome | Rheumatoid Arthritis | Liver Failure | Non-small Cell Lung Cancer | Porphyria Cutanea Tarda | IgA Deficiency | Keloid | Fibromyalgia | Aneurysm, Abdominal Aortic | Osteochondrosis | Cardiospondylocarpofacial Syndrome | Schindler Disease | Anencephaly | Keratoacanthoma | Diffuse Mesangial Sclerosis | Greenberg Dysplasia | Allergic Contact Dermatitis | Spinal Cord Diseases | Syndactyly | Aldosterone Synthase Deficiency | Ependymoma | Infectious Diarrhea | Low Phospholipid Associated Cholelithiasis | Atelosteogenesis Type 2 | Rash | Neurofibroma | Metaphyseal Chondrodysplasia, Schmid Type | Creatine Deficiency Syndrome | Non-epidermolytic Palmoplantar Keratoderma | Joubert Syndrome 2 | Down Syndrome | Congenital Lipoid Adrenal Hyperplasia | Nemaline Myopathy 8 | Pericarditis | Neuromuscular Disorders | Waardenburg Syndrome Type 4 | Tendinopathy | Long QT Syndrome Type 1 | Malaria | Imerslund-Grasbeck Syndrome | Spinocerebellar Ataxia Type 1 | Wieacker-Wolff Syndrome | Juvenile Myoclonic Epilepsy | Lipid Metabolism Disorders | Pycnodysostosis | Desmosterolosis | Hypertelorism | Cousin Syndrome | Cerebellar Ataxia, Cayman Type | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Membranous Nephropathy | Pulmonary Alveolar Proteinosis | Absence Epilepsy | Sick Sinus Syndrome | Neurofibromatosis | Melnick-Needles Syndrome | GLUT1 Deficiency Syndrome | Cyst | Restless Legs Syndrome | Ehlers-Danlos Syndrome | Autosomal Recessive Spastic Paraplegia Type 35 | Open-angle Glaucoma | Myelodysplasia | Thrombotic Microangiopathy | Cutaneous Lupus Erythematosus | Pleomorphic Xanthoastrocytoma | Hemophilia | Rubeosis Iridis | Ileitis | Sclerosteosis | Macrodactyly | Klinefelter Syndrome | Clouston Hidrotic Ectodermal Dysplasia | Lassa Fever | Congenital Generalized Lipodystrophy | Osteoporosis-pseudoglioma Syndrome | Acute Lymphocytic Leukemia | Intestinal Obstruction | Myasthenia | Hepatic Veno-occlusive Disease | Danon Disease | Cardiofaciocutaneous Syndrome | B-cell Chronic Lymphocytic Leukemia | Glycogen Storage Disease Type 0, Muscle | Uveitis | Polyradiculopathy | Prune Belly Syndrome | Hyperbilirubinemia, Neonatal | Glycogen Storage Disease Type 3 | Amblyopia | Pancreatitis, Chronic | Polycythemia | Cocaine-Related Disorders | Familial Advanced Sleep Phase Syndrome | Hodgkin Lymphoma | Melanoma, Uveal | Aphasia | Ophthalmia, Sympathetic | Craniolenticulosutural Dysplasia | Milk Allergy | Arteriovenous Malformations | Multisystemic Smooth Muscle Dysfunction Syndrome | Fatty Aldehyde Dehydrogenase Deficiency | Retinopathy Of Prematurity | Acute Chest Syndrome | ADNP Syndrome | Myofibromatosis | Diastrophic Dysplasia | Diabetes Insipidus, Nephrogenic | Microcephaly, Seizures, And Developmental Delay | Hyperlipidemia, Familial Combined | Familial Hyperaldosteronism | Pseudohypoaldosteronism | Usher Syndrome Type IIC | Vascular Cognitive Impairment | Immunoproliferative Disorders | Pilomatrix Carcinoma | Epidermolysis Bullosa Dystrophica | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Macular Corneal Dystrophy | Neuropathy | Congenital Nystagmus | Tonsillitis | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Von Willebrand Disease | Diarrhea | Norrie Disease | Azoospermia | Moyamoya Disease | Pseudohypoparathyroidism Type 2 | Glioblastoma | Metabolic Diseases | Cri-du-chat Syndrome | Lipid Storage Diseases | Obsessive-compulsive Disorder | FG Syndrome | Scleritis | Donnai-Barrow Syndrome | Glaucoma | Leri Pleonosteosis | Charcot-Marie-Tooth Disease, Type 2C | Erythrokeratodermia Variabilis | Primary Sclerosing Cholangitis | Benign Hereditary Chorea | Hepatitis, Autoimmune | Focal Dermal Hypoplasia | Intracerebral Hemorrhage | Glioblastoma Multiforme | Cutaneous T-cell Lymphoma | Blepharospasm | Oculocutaneous Albinism Type 4 | Early Infantile Epileptic Encephalopathy | Lysosomal Acid Lipase Deficiency | Malnutrition | Hyperparathyroidism | Still Disease | Teratozoospermia | Lattice Corneal Dystrophy | Holt-Oram Syndrome | Myelitis | Fragile X Syndrome | Non-Langerhans Cell Histiocytosis | Idiopathic Multicentric Castleman Disease | Optic Neuropathy, Anterior Ischemic | Bainbridge-Ropers Syndrome | Charcot-Marie-Tooth Disease, Type 6 | Neurofibromatosis Type 1 | VACTERL/VATER Association | Orthostatic Intolerance | Hennekam Lymphangiectasia-lymphedema Syndrome | Lymphangioleiomyomatosis | Infantile Refsum Disease | Sarcoma, Ewing | Erdheim-Chester Disease | Subcortical Band Heterotopia | Stomatitis | Kabuki Syndrome | Adenylosuccinate Lyase Deficiency | Facioscapulohumeral Muscular Dystrophy Type 1 | Pemphigoid | Wolff-Parkinson-White Syndrome | AIDS Dementia Complex | Gardner Syndrome | Ocular Hypertension | Congenital Ichthyosiform Erythroderma | Nephroblastoma | Celiac Disease | Iron Deficiency Anemia | Muir-Torre Syndrome | Microvillus Inclusion Disease | Polycystic Liver | Charcot-Marie-Tooth Disease, Type 2A | Carney-Stratakis Syndrome | Intestinal Pseudo-obstruction | Charcot-Marie-Tooth Disease, Type 1A | Neurocysticercosis | Essential Fructosuria | Chondrosarcoma | Iron Overload | Ichthyosis Hystrix, Curth-Macklin Type | Otosclerosis | Zollinger-Ellison Syndrome | Geleophysic Dysplasia | Depression | Palsy, Cerebral | Hyperinsulinism-hyperammonemia Syndrome | HANAC Syndrome | Pseudohermaphroditism | Mast Cell Leukemia | Chronic Neutrophilic Leukemia | Coronary Artery Disease | Glutaric Aciduria Type 3 | Delayed Sleep Phase Syndrome | Corneal Edema | Sporadic Hemiplegic Migraine | Psoriasis | Adrenoleukodystrophy, X-linked | Cancer, Bladder | Epidermolytic Ichthyosis, Annular | Acute Myeloid Leukemia | Combined Pituitary Hormone Deficiency | Facioscapulohumeral Muscular Dystrophy | Wiskott-Aldrich Syndrome | Prediabetes | Cartilage Disorders | Fanconi Syndrome | Leiomyosarcoma | Retinoblastoma | Kashin-Beck Disease | Hypogammaglobulinemia | Poirier-Bienvenu Neurodevelopmental Syndrome | Familial Pheochromocytoma-paraganglioma | Axenfeld-Rieger Syndrome | Tracheal Disorders | Mabry Syndrome | Osteosarcoma | Cataract | Asperger Syndrome | Specific Granule Deficiency | Subacute Sclerosing Panencephalitis | Echinococcosis | Osteosclerosis | Epilepsy Of Infancy With Migrating Focal Seizures | Glycogen Storage Disease Type 1 | Sleep Apnea, Obstructive | Odonto-onycho-dermal Dysplasia | Hemangioblastoma | Neurofibromatosis-Noonan Syndrome | T-cell Leukemia | Postaxial Polydactyly | 3-methylglutaconic Aciduria | Xeroderma Pigmentosum | Knobloch Syndrome | Congenital Nephrotic Syndrome | Dermatitis Herpetiformis | Waardenburg Syndrome Type 2E | Asthma, Exercise-induced | Pseudomyxoma Peritonei | Renal Tubular Dysgenesis | Neuroleptic Malignant Syndrome | Sepiapterin Reductase Deficiency | Pseudohypoparathyroidism Type 1C | Congenital Hereditary Endothelial Dystrophy Type II | Myocardial Infarction | Posterior Polar Cataract | Li-Fraumeni Syndrome | Pyoderma Gangrenosum | Brachial Plexus Neuropathy | Pulmonary Stenosis | Cannabis Abuse | Twin-to-twin Transfusion Syndrome | Hereditary Multiple Exostoses | Blomstrand Osteochondrodysplasia | Familial Dysautonomia | Glioma | Familial Retinal Arterial Macroaneurysm | Thanatophoric Dysplasia | Takayasu's Arteritis | Melanocytic Nevus | Corneal Dystrophy And Perceptive Deafness | Constipation | Amenorrhea | Fibrillation, Atrial | Thyroid Dyshormonogenesis | Uveitis, Anterior | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Facioscapulohumeral Muscular Dystrophy Type 2 | Prurigo Nodularis | Eczema | Benign Recurrent Intrahepatic Cholestasis 1 | Cryopyrin-associated Periodic Syndromes | Hereditary Mixed Polyposis Syndrome | Desbuquois Syndrome | Pelizaeus-Merzbacher Disease | Spinal Muscular Atrophy | Blastomycosis | Tietze Syndrome | Multiple Sclerosis, Primary Progressive | Carcinoma, Squamous Cell | Oculodentodigital Dysplasia | Premenstrual Syndrome | Patent Foramen Ovale | Discoid Lupus Erythematosus | Arthrogryposis | Dystrophy, Cone-rod | Disseminated Superficial Actinic Porokeratosis | Schnitzler Syndrome | Epidermolysis Bullosa Simplex, Localized | Nail Disorder, Nonsyndromic Congenital | Retinopathy, Diabetic | Heart Septal Defects | Zellweger Syndrome | Cranial Nerve Disease | Panuveitis | Progressive Myoclonic Epilepsy | Rhinitis | T-cell Prolymphocytic Leukemia | Eating Disorder | HELLP Syndrome | Angiomyolipoma | Hyperhomocysteinemia | Autism | Infertility | Carcinoma, Signet Ring Cell | Williams Syndrome | Hyperthyroidism | Atrioventricular Septal Defect | Esophageal Carcinoma | Pyruvate Carboxylase Deficiency Disease | Thrombophlebitis | Chromosome 9q34.3 Deletion Syndrome | Congenital Poikiloderma | Ataxia-ocular Apraxia 2 | Keratosis, Actinic | Sleep Apnea, Central | Encephalopathy, Ethylmalonic | Triphalangeal Thumb-polysyndactyly Syndrome | Alcoholism | Ulcerative Colitis | Peeling Skin Syndrome Type B | Encephalocele | Primary Familial Brain Calcification | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Tetanus | Pearson Syndrome | Hereditary Elliptocytosis | Fahr Disease | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Limb Girdle Muscular Dystrophy | Osteoglophonic Dysplasia | Choriocarcinoma | Lymphoma | Inflammatory Linear Verrucous Epidermal Nevus | Raynaud Phenomenon | Primary Hyperoxaluria | Synpolydactyly | Xeroderma Pigmentosum Variant Type | Perivascular Epithelioid Cell Tumor | Hereditary Neuropathy With Liability To Pressure Palsies | Leukemia-lymphoma, Adult T-cell | Herpes Genitalis