Disease

Interstitial Lung Diseases

About the Disease
Interstitial Lung Disease, also known as ild, is related to interstitial pneumonitis, desquamative, familial and rheumatoid arthritis interstitial lung disease, and has symptoms including shortness of breath, coughing and hemoptysis. An important gene associated with Interstitial Lung Disease is INPP5E (Inositol Polyphosphate-5-Phosphatase E), and among its related pathways/superpathways are Innate Immune System and Metabolism of proteins. The drugs Prednisone and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include lung, bone marrow and skeletal muscle, and related phenotypes are homeostasis/metabolism and neoplasm

Common Targets
P2RX1 | HLA-A | LPAR1 | ALOX5AP | GLIS3 | TGFBR1 | D21S2088E | G3480 | FARSB | XDH | G7422 | LINC01239 | NKX2-1 | G7015 | MMP12 | Tyrosine Kinase (nonspecified subtype) | IVD | AQP4 | CTLA4 | NF-kappaB (NFkB) | SFTPA1 | CCN2 | HER (erbB) (nonspecified subtype) | SERPINE1 | SSH2 | NOX4 | CHIT1 | PDGFRA | PDE5A | CD86 | TOLLIP | KIT | ITGA3 | FARSA | Interleukin-12 (IL-12) | IFNG | DSP | SFTPC | DDR1 | STAT4 | NOX3 | LIPC | TGFB1 | Transforming growth factor beta (nonspecified subtype) | RTEL1 | HLA-DQB1 | Triacylglycerol Lipase (TG Lipase) (nonspecified subtype) | ABL1 | CD80 | PON1 | NADPH Oxidase Complex | Nitric oxide synthase (NOS) (nonspecified subtype) | IL6R | LOXL2 | HLA-DPB1 | MIR3667HG | Integrin alphavbeta6 receptor | SFTPA2 | SFTPD | HLA-C | LINC01276 | AGTR2 | G6774 | PDGFRB | Cytochrome P450 Enzymes (nonspecified subtype) | CSF1R | MARS1 | NADPH Oxidase (nonspecified subtype) | HLA-DRB1 | CCL18 | MEP1A | NOX1 | GRIN2B | MEP1B | LIPE | DAGLA | ELANE | G5243 | G4780 | SLC25A48 | CCSER1 | PDE4D | PORCN | LTC4S | HLA-B | TGFB3 | GRN | ABCA3 | Integrin alphavbeta8 Receptor | CMA1 | RPA3 | TSHZ2 | FGFR3 | LIPG | G7124 | TYK2 | TNFRSF13B | HABP4 | ENPP2 | SPP1 | G3569 | CACNA1H | Integrin alphavbeta3 (vitronectin) receptor | KDR | ZC3H12A | PDE4B | UMAD1 | HLA-DQA1 | BRD4 | G9429 | FLT4 | FGFR1 | FLT1 | TSNARE1 | PREP | SNAI3-AS1 | IKBKB | VDR | ZNF664-RFLNA | VAMP1 | PARN | ALDH2 | BCR | G1950 | Folate Receptor (nonspecified subtype)

疾病靶点研报
Interstitial Lung Diseases

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