Bladder Cancer

About the Disease
Bladder Cancer, also known as urinary bladder cancer, is related to bladder urothelial carcinoma and costello syndrome. An important gene associated with Bladder Cancer is FGFR3 (Fibroblast Growth Factor Receptor 3), and among its related pathways/superpathways are Breast cancer pathway and MAPK Signaling: Mitogens. The drugs Tamsulosin and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include urinary bladder, lymph node and prostate, and related phenotypes are transitional cell carcinoma of the bladder and bladder neoplasm

Common Targets
GRIK5 | TJP2 | KLHL34 | NDUFA9 | ACTA2 | ANKRD12 | SLX4 | CSNK1E | EGFR-AS1 | BIVM-ERCC5 | XPC | CDH13 | SRGAP3 | LAMA5 | DST | STN1 | UGT1A10 | TRIM3 | CASP7 | CBR3 | DPM2 | CSMD3 | LRP6 | EPCAM | MATN3 | MACF1 | PLD3 | SERPINB5 | MGST1 | ECRG4 | HDAC2 | CLK3 | IL12B | SPTSSB | G3620 | CACNA1B | HDAC6 | CD248 | SDC1 | TLR3 | ERCC1 | TSC1 | COPS2 | FOXE1 | MIR6766 | G5133 | PLPP7 | G595 | KIT | THBS1 | KNL1 | Carbonic Anhydrase (nonspecified subtype) | SOCS1 | ENOSF1 | TFRC | TNFRSF1B | POLR1HASP | CHAF1B | PXK | RHOBTB2 | ATG2B | FADS2 | FARS2 | PTGES | LRRK2 | BDNF | IREB2 | Heat shock protein 90 (nonspecified subtype) | ASXL1 | ONECUT2 | NECTIN4 | PRMT6 | IL1RN | ANGPTL4 | PIGP | SLIT2 | N4BP1 | Integrin alphavbeta3 (vitronectin) receptor | MAGEA4 | TRIM29 | HORMAD2 | G29126 | SCN7A | EID2 | EOMES | ANKRD13B | SFN | PMF1 | KCNA3 | NF-kappaB (NFkB) | IRX2-DT | SREBF2 | MIR33A | TGFB1 | WNT8A | CTAG1A | SLC24A2 | CCND2 | GDF15 | CSF1R | NEIL2 | CAMK1 | LILRB4 | SFRP2 | CD3 Complex (T Cell Receptor Complex) | G207 | GRM5 | KISS1 | ZNF788P | ZBTB17 | Ribonucleoside-diphosphate reductase | MAX | ELANE | WNT8B | GATA4 | PLOD1 | TNFRSF10A | PRMT8 | MIR23A | G5728 | HRAS | LCN8 | RGS9BP | PLXNB2 | UGT1A8 | PRMT5 | CYP2C19 | LMLN | ERCC6 | FAT1 | THNSL2 | KMT2C | GAS5 | SOX1 | TOP1 | PHF11 | HOXA9 | CDK4 | HOXB13 | HPCAL1 | Cyclin-dependent kinase (nonspecified subtype) | G673 | ALKBH2 | IL2RA | G7099 | NR1H2 | XRCC2 | ZFP30 | VPS35 | TBR1 | VIM | ABCC5 | RAD52 | SPPL3 | DMPK | MAGEA9 | CTC1 | SYT15 | NAT2 | MUC16 | DMC1 | G7295 | GLT8D2 | FBLN1 | ADGRF5 | PDCD11 | CASC11 | HAGH | MIR137 | KDM4C | GALNT8 | PCNP | IFNGR1 | GFRAL | Protein kinase C (nonspecified subtype) | POLE | SCGB3A1 | G598 | SLC39A11 | IL17RA | SF3B4 | G1950 | KCND3 | BRCA2 | VEGFC | FBXO46 | SOX17 | RUNX3 | SLCO2B1 | T-Type Calcium Channel | SPAM1 | SYNPO2 | HLTF | ZSCAN12 | IL10RA | MMP3 | G1029 | G4780 | RFFL | IGFALS | FGFR3 | DDR2 | IRX1 | UQCC6 | ALDH2 | PSCA | IRS2 | MAP2K1 | IRAK3 | IL4R | G6352 | MIR206 | ERBB3 | FZD4 | DROSHA | CCNB1IP1 | DNA Topoisomerase II (nonspecified subtype) | MUTYH | PDGFRB | PMS2 | IHO1 | SLC22A31 | SLC14A1 | PLA2G15 | NR1H3 | TESK2 | TRPC5 | NCAM2 | Steroid 5-alpha-Reductase (nonspecified subtype) | RRM2 | PRDM2 | MICALCL | GLI3 | SNX8 | LOC105373659 | NDUFV2 | GEMIN4 | CHD5 | LIN7A | RAB37 | PIK3CB | EED | GSTA1 | UGT1A7 | TNFRSF18 | CACNA1G | BAK1 | SALL1 | LINC00643 | LRP5 | VPS8 | GSTO1 | HS3ST2 | Fc-gamma Receptor (FCGR) (nonspecified subtype) | TBCD | TP73 | G142 | SORCS3 | PEG3 | AP3D1 | MMP12 | PCDH17 | NCF2 | PRDM14 | DCK | TCF4 | PIM3 | DBH | TNFSF11 | ALX1 | COMT | OGG1 | ADGRE3 | IRS4 | CHFR | CD44 | TDRD9 | SPARC | RSPH6A | DLC1 | TACC3 | ICAM1 | Fibroblast growth factor (FGF) (nonspecified subtype) | JSRP1 | MIR24-2 | FOXD3 | HDAC3 | TNFSF10 | CD14 | GSTA2 | ADORA1 | LAMB3 | PCDH8 | CERKL | ATP5MC2 | DNAJC15 | Glutamate Transporter (nonspecified subtype) | NKX6-2 | MIR143 | RGPD8 | G23411 | TMEFF2 | NAT1 | HDAC1 | LY75 | EGR2 | ASPH | MYO16 | SYN3 | UGT2B4 | ILDR1 | WIF1 | G4609 | FHIT | HPDL | CD40 | SFRP4 | ABCA1 | G2475 | FZD7 | G7157 | MFF | Estrogen receptor (nonspecified subtype) | BNIP3 | NUDT1 | MIR23AHG | IL-4 receptor | CYP2E1 | TP63 | CEBPZ | STK31 | CELSR3 | TSC2 | FLT4 | NRN1 | CWC27 | MFSD6L | NKTR | SOD2 | MIR605 | ZFHX3 | CASP8 | SEPTIN9 | Tyrosine Kinase (nonspecified subtype) | EHBP1 | TBX3 | CFAP43 | PRRX1 | GPX1 | PTPN13 | Reverse transcriptase (Telomerase) | MIR423 | DNAH6 | MIR21 | C7orf50 | DGCR8 | IL32 | PCDH10 | ABCC2 | ILDR2 | ARNT | ARHGAP28 | PPARG | CDC27 | ZNF154 | POLQ | MKI67 | PRMT1 | BUB1 | TGFBR1 | PENK | GATA2 | HELQ | DNMT3B | FGF9 | G999 | TMTC2 | VSX1 | HLA-A | ID4 | IL27 | MON1A | HSD11B1 | ADORA2A | IL12RB2 | G3605 | STK11 | PKHD1 | B3GAT1 | CBR1 | DNAH1 | CYP2W1 | FLT1 | GPC1 | AKT2 | GSTT1 | SMG7 | ARHGEF4 | SCT | TIE1 | MPG | XRCC3 | SLC22A2 | TPD52 | PAX5 | ADH1B | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | KLC3 | HM13 | PTOV1 | HLX | BIRC6 | TMEM106A | G3480 | TBX2 | TDG | ARVCF | UGT1A6 | C19orf47 | DAPK1 | NPY | PYCARD | GSTO2 | MMP7 | PPP1R13L | Interferon (nonspecified subtype) | Voltage-Gated Sodium Channel Complex | G2309 | DICER1 | PLXDC2 | PRF1 | CERS2 | ADGRG6 | SMYD3 | Tubulin | LSP1 | ERCC2 | NIPBL | AATK | CXCL12 | OSGEP | ERCC3 | PIK3C2G | SPTB | ZNF655 | SPATA6L | TLR2 | PCBP2-OT1 | TCF7 | KRT13 | G2099 | PLEKHS1 | LRRC27 | PLA2G6 | HIC1 | ANKRD30B | G836 | CCND3 | HOXB2 | TFAP2B | EEF1A1 | NCL | FOXF2 | WWTR1 | WASHC3 | BLTP1 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | FANCI | GATA5 | MIR124-2 | MRM2 | INSRR | FDPS | NEDD9 | PADI3 | CXCR3 | RPPH1 | PNP | PRKDC | PTGER4 | PNKP | BCL9 | G4318 | POLG | CLDN6 | PCDHGA4 | RAF1 | KMT2A | CACNG1 | HMCN1 | MIR3620 | HCRTR2 | SLC17A1 | G2033 | WDR59 | XPO5 | RARB | KCNA6 | KIF11 | TBX5 | FGFR4 | BDNF-AS | CXCL1 | MIR27A | HEPACAM | ZNF671 | PAM | HERC1 | KDM1A | CYP1A2 | AKT1S1 | IL18RAP | PPP1CB | GAU1 | HDAC4 | TEK | NUPR1 | AKR1C3 | SPTBN1 | CD3E | CDKN2AIP | RB1 | G4193 | MUC2 | DNAJB2 | PRUNE2 | WTAPP1 | STAT4 | FCN1 | POU4F2 | CCNE1 | SF3A1 | RAB15 | G4233 | Sodium channel (nonspecified subtype) | BRPF1 | HCG9 | IL1RAP | RXRA | CYP3A5 | G2064 | PIK3CA | AP3S2 | CTH | PKM | CSF2 | EEF1A2 | BTG4 | HTR3B | CD80 | APEX1 | TOE1 | TDRD10 | CRYGD | ABCC6 | EPHA2 | CCNA1 | CTLA4 | SULT1A2 | MIR124-3 | EP400 | RIMS1 | PIM1 | BRSK2 | FSIP2 | UNC5C | FASN | ZNF365 | CLPTM1L | ZBTB46 | PDE2A | TINCR | G7124 | BARHL2 | FLT3 | G5743 | SYN1 | IL2 | TDO2 | USH2A | AXIN2 | MIR4483 | THEM4 | XRCC4 | GYS1 | TESMIN | KCNK9 | POLR2A | NOS3 | NRAP | FASLG | CTAG1B | GSC | MIER3 | MMP2 | CDKN1B | CCT6B | G196 | MAP2K2 | IRF8 | CRISPLD2 | USP30 | HK2 | WT1 | PAX6 | G5243 | FGFRL1 | G367 | TIGIT | RSPH9 | TMEM121 | NELFB | VRK1 | PON1 | PARP2 | MYOM3 | G1786 | TBX15 | AS3MT | TYMS | RBL2 | RET | SIN3A | TTLL5 | TLR9 | SHH | CACNA1A | EFCAB12 | ACYP2 | G672 | NOX3 | PDE5A | F2RL3 | GPR83 | ZBTB3 | SNX25 | DCHS2 | CLDN4 | ADAMTS18 | PALB2 | ABHD17B | NT5E | CABP2 | RAD51L3-RFFL | FEZF2 | CD47 | METAP2 | Focal Adhesion Kinases (FAK) (nonspecified subtype) | FAS | MIR146A | MGMT | MMP8 | TOP2A | ZAR1 | CCDC81 | ELF3 | PHF7 | MASP1 | HPSE | HS1BP3 | ARF1 | LRP2 | RNF213-AS1 | PTOV1-AS2 | IL10 | TRIM67 | CSAD | KDR | MLLT3 | BIRC5 | Cyclin-dependent kinase inhibitor (nonspecified subtype) | SMAD3 | MTHFR | MANF | MIR4749 | SERPIND1 | SLCO1B1 | ITIH5 | USP45 | IFNG | G6776 | NOS2 | EGLN1 | IL18R1 | WDFY3 | KMT2D | CADM1 | FYN | ZIC4 | ZNF577 | LRP1B | NAAA | SFRP1 | FNTB | CCR5 | DSCAM | G1956 | NOTCH2 | GSTM1 | RIC1 | LRRC4C | CREBBP | CTSB | TACSTD2 | CHURC1-FNTB | CFTR | Arginase (nonspecified subtype) | UMPS | BAMBI | VHL | Proteasome Complex | SHISA8 | MYO3A | ALKBH8 | STING1 | UBXN2B | DHFR | NQO1 | XPA | ACOT13 | SIM2 | SLC7A4 | CYP1B1 | EPRS1 | TWIST1 | NID2 | CAPS2 | PMAIP1 | LOC101927421 | PRKAR2B | MIF | SMUG1 | ARID1A | VAX2 | CREB3L3 | TNFRSF14 | PARP4 | MIR9-3 | SALL3 | PIP4P1 | MBD4 | ANK3 | GSTP1 | NADPH Oxidase Complex | CCL2 | PINLYP | TFPI | TTC3 | G7422 | WDFY4 | G2146 | BAP1 | UGT1A1 | CDX2 | TENT4B | SLC11A1 | LRP8 | TXNDC16 | ANKRD24 | AHSG | MIR663A | H2AX | IL6R | MIR196A2 | ROR2 | VSIG2 | MAP1LC3A | G3845 | LIG3 | APC | FMN1 | RARG | ELF4 | TNFRSF1A | CDK12 | VSIR | MYBPC2 | CD276 | OPCML | H4C6 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | IL4 | CD19 | CHEK2 | TMEM240 | XRCC1 | MRTFA | 11beta-Hydroxysteroid Dehydrogenase (nonspecified subtype) | CRP | ALDH1A3 | PRAC1 | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | PLAUR | NCOA1 | G596 | GPER1 | RASSF1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | MSH2 | G472 | CRBN | MIR5009 | IRS1 | GALR1 | G5347 | MSH6 | MLH1 | MARCHF11 | DOCK10 | TNFRSF9 | RHBDF1 | EPAS1 | ADGRL3 | TGFBR2 | SLCO1B3 | IRAG1 | H19 | FBXW7 | SSC4D | MIR6836 | TRPM5 | HLA-C | TLR7 | CCNK | NADPH Oxidase (nonspecified subtype) | WNT3 | OTX1 | PLPP3 | IL18 | IL23R | DCC | ODC1 | RPS6KA5 | ITGB6 | SIX3 | PRSS57 | AHRR | MMP15 | UNG | NGF | PTGER2 | G7015 | ABCC11 | TNFRSF10B | HK3 | MMP1 | PDE3A | DNA Methyltransferase (DNMT) (nonspecified subtype) | GRIN2B | G6714 | STAG2 | GPRC5A | LIG4 | DPYD | VTCN1 | LNCPRESS1 | EVX2 | SIRT6 | INKA2 | G3576 | NFKB1 | KISS1R | PITX2 | CDH16 | IL1B | RIGI | E2F1 | MPO | ERCC5 | NBN | RARRES1 | G3569 | NHERF2 | OR51L1 | ACTB | TIMP3 | HSP90B1 | ZP3 | DMRTA2 | KDM6A | PAWR | MAGEA9B | NCOA3 | PON3 | MYNN | ISL1 | MST1R | LINGO2

Note: If you'd like to get a target analysis report for Bladder Cancer, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Bladder Cancer at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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