Lymphoproliferative Disorders

About the Disease
Immune Dysregulation with Autoimmunity, Immunodeficiency, and Lymphoproliferation, also known as autoimmune lymphoproliferative syndrome due to ctla4 haploinsuffiency, is related to pontocerebellar hypoplasia, type 14 and pontocerebellar hypoplasia, type 15, and has symptoms including diarrhea An important gene associated with Immune Dysregulation with Autoimmunity, Immunodeficiency, and Lymphoproliferation is CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4). The drugs Basiliximab and Hematinics have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, t cells and lung, and related phenotypes are splenomegaly and hepatomegaly

Common Targets
COL12A1 | GOT2 | MPZL1 | ADK | MATN3 | INPPL1 | NDUFA10 | IL27RA | FADD | MUC19 | TRIM4 | GRAP2 | MAP1B | ZNF436-AS1 | ERCC6L2 | NBPF1 | SLC18A2 | WNT7B | ZNF660 | MAX | CHD1 | RSF1 | CHM | CADM2 | BRF1 | DKC1 | TLN2 | VPS13B | DDX11 | ADCY3 | KRT72 | METTL22 | CTDSP2 | CACNA1G | PPP2R1A | ASXL3 | XIAP | MYO19 | TMEM67 | TJP1 | UNC13D | IL12RB1 | CORO1A | HTRA1 | TUBA3D | ADGRB1 | LCA5 | CTRB1 | TUBA3C | LGALS8 | MND1 | USP14 | FKTN | HTATIP2 | TET2 | SIRPA | G5243 | MTHFD2 | ADGRL2 | G367 | RAB12 | SOX8 | HECTD2 | ZAP70 | SETMAR | GCKR | LRCH3 | EPG5 | MXD1 | ACSM5 | ANKRD36C | RDH5 | EFEMP1 | KCNA5 | MS4A1 | SMAD9 | NOS3 | PRF1 | PFKM | AASS | ASIC5 | MICU3 | POLG | H6PD | HMGCS2 | G5747 | SLC66A3 | C2CD6 | ARAF | ARSD | SDR42E2 | CACNA1D | PDPR | NRXN1 | PTPRN | MAGT1 | QSOX1 | G3845 | SNAI1 | FASLG | GALNT11 | NLRC4 | NF1 | LAMA2 | TRBV24-1 | TMEM127 | CCDC88A | GJC2 | CIDEA | CFTR | FIGN | BARHL2 | RYR3 | CDCA2 | MDN1 | PON1 | SNAP91 | KCNT1 | GRM1 | FBLN2 | ATP12A | ABCF1 | RBM39 | GFM2 | G3082 | POTEG | MAP10 | RAB3IL1 | SETD1A | TPSB2 | STING1 | SLC7A13 | SLC25A51 | GPBP1 | DRD3 | CFH | TRIO | HNF4A | COL20A1 | SLC7A2 | FUT2 | GABRA2 | POLR1B | KCTD1 | ATP4A | LRP1B | BTAF1 | CLVS2 | MCRS1 | WDFY3 | ALG8 | NECTIN2 | MTFP1 | ACTC1 | TNFRSF1A | FGF14 | DDX3X | PEAR1 | HOXC9 | RXRG | SETD1B | INPP5A | SCN5A | HNF1B | EGFLAM | TCF7L2 | GSPT2 | SLC17A7 | DEFA7P | AQP1 | SPOCD1 | CDH23 | WDR20 | ADGRL3 | CYLD | TAOK2 | PAXIP1 | CPZ | CDC25B | NCKAP5 | COL6A6 | TTC26 | GABRA3 | CBFB | WDR25 | HSP90B1 | F8 | CA4 | PRORY | CTBP2 | G673 | FOXD4L3 | ZBTB48 | VWA1 | SPP1 | GINS3 | COL3A1 | CNTN5 | GOT1

Note: If you'd like to get a target analysis report for Lymphoproliferative Disorders, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Lymphoproliferative Disorders at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Keratosis, Actinic | Sulfite Oxidase Deficiency | Osteosclerosis | Gingivitis | Hypertension, Renal | Camptocormia | Osteogenesis Imperfecta | Gastroschisis | Familial Exudative Vitreoretinopathy | Tyrosinemia Type 1 | 3-methylglutaconic Aciduria Type IV | Primary Progressive Nonfluent Aphasia | Membranous Nephropathy | Pyruvate Decarboxylase Deficiency | Tuberculosis | Hypolipoproteinemia | Adenosine Deaminase Deficiency | Hemoglobinopathies | Hypersensitivity Pneumonitis | Cardiomyopathy, Peripartum | Tonsillitis | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Conn Syndrome | Apraxia | Paget's Disease Of The Breast | Pleomorphic Xanthoastrocytoma | X-linked Charcot-Marie-Tooth Disease | Ichthyosis, X-linked | Primary Progressive Aphasia | Sleep Apnea, Obstructive | Vitreoretinopathy, Proliferative | Hemimegalencephaly | Cardiac Arrest | Disseminated Intravascular Coagulation | Goiter, Nodular | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Gnathodiaphyseal Dysplasia | Cerebellar Ataxia, Cayman Type | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Mitochondrial Encephalomyopathy | Precocious Puberty | Eiken Syndrome | Trimethylaminuria | Goiter | Oral Lichen Planus | Corneal Ulcer | Congenital Dyserythropoietic Anemia Type 1 | Optic Nerve Diseases | Hypertrophy | IMAGe Syndrome | Cardiospondylocarpofacial Syndrome | Mitochondrial Myopathy | Rift Valley Fever | Histiocytosis | Mevalonate Kinase Deficiency | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Muscle Wasting | Retinal Vasculitis | Sjogren Syndrome | Senior-Loken Syndrome | Achondrogenesis | Neurofibromatosis Type 2 | Pseudo-pseudohypoparathyroidism | Neuroleptic Malignant Syndrome | Schnitzler Syndrome | Binge Eating Disorder | Fuchs Heterochromic Iridocyclitis | Hypohidrotic Ectodermal Dysplasia, X-linked | Glycogen Storage Disease | Veno-occlusive Disease | COACH Syndrome | Primrose Syndrome | Restless Legs Syndrome | Adenoma, Villous | Ocular Albinism Type 1 | Vitreoretinal Degeneration, Snowflake Type | Thin Basement Membrane Disease | Retinitis Pigmentosa | Smith-Magenis Syndrome | Peripheral Neuropathy | Mitochondrial DNA Depletion Syndrome | Tay-Sachs Disease | Congenital Bilateral Absence Of Vas Deferens | Retinopathy, Diabetic | Huntington's Disease | Hypersensitivity | Meningococcal Meningitis | Localized Scleroderma | Papillorenal Syndrome | Polymyalgia Rheumatica | Endophthalmitis | Lung Diseases | Hodgkin Lymphoma | Ataxia-ocular Apraxia 2 | Aicardi-Goutieres Syndrome | Premature Ejaculation | Neonatal Progeroid Syndrome | Fatty Aldehyde Dehydrogenase Deficiency | Autosomal Recessive Spastic Paraplegia Type 75 | Lupus Erythematosus | Facioscapulohumeral Muscular Dystrophy Type 1 | Behavioral Variant Of Frontotemporal Dementia | Dementia | Carney Triad | Chediak-Higashi Syndrome | Primary Ovarian Insufficiency | Acrocallosal Syndrome | Encephalopathy, Glycine | Macrodactyly | Hyperbilirubinemia | Bardet-Biedl Syndrome | Mesothelioma, Malignant | Unverricht-Lundborg Syndrome | Extramammary Paget's Disease | Spinocerebellar Ataxia Type 8 | Diabetes Insipidus | Zellweger Syndrome | Posterior Polar Cataract | Rash | Schistosomiasis Mansoni | Adrenal Insufficiency | Globozoospermia | Neurotoxicity | Carbohydrate Metabolism Disorders | Pseudohypoaldosteronism | Vitamin B12 Deficiency | Malonyl-CoA Decarboxylase Deficiency | Hyperphosphatasia With Intellectual Disability Syndrome 4 | ACTH-independent Macronodular Adrenal Hyperplasia | Waardenburg Syndrome Type 2A | Seminoma | Gerstmann-Straussler-Scheinker Syndrome | Diffuse Palmoplantar Keratoderma | McCune-Albright Syndrome | Dyggve-Melchior-Clausen Disease | Biotinidase Deficiency | Chorioretinitis | Cerebrotendinous Xanthomatosis | Atrial Septal Defect | Encephalopathy | Craniopharyngioma | Hepatitis, Autoimmune | Osteoporosis-pseudoglioma Syndrome | Arterial Tortuosity Syndrome | Tremor | X-linked Acrogigantism | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Autoimmune Disease | Postpoliomyelitis Syndrome | Camurati-Engelmann Disease | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Histiocytic Sarcoma | Metachondromatosis | Basal Cell Nevus Syndrome | Glomerulonephritis | Harlequin Ichthyosis | Hidradenitis Suppurativa | Hyperuricemic Nephropathy, Familial Juvenile | Distal Myopathy | Atelosteogenesis Type 2 | Arthritis, Gouty | Osteogenesis Imperfecta Type II | Schnyder Crystalline Corneal Dystrophy | Familial Mediterranean Fever | Crigler-Najjar Syndrome | Acute Myeloid Leukemia | Erysipelas | Portal Vein Thrombosis | Sialoadenitis | Maternally Inherited Diabetes And Deafness | CHARGE Syndrome | Pilomatrix Carcinoma | Carcinoma, Small Cell | Bladder Exstrophy | Congenital Primary Aphakia | Progressive Familial Intrahepatic Cholestasis Type 3 | Oculocutaneous Albinism Type 4 | Hypobetalipoproteinemias | Dysferlinopathy | T-cell Prolymphocytic Leukemia | Pleurisy | Cornelia De Lange Syndrome | Autosomal Recessive Spastic Paraplegia Type 35 | Multiple Sclerosis, Primary Progressive | Primary Erythromelalgia | Ocular Hypertension | Periventricular Leukomalacia | Corneal Dystrophy And Perceptive Deafness | Neuroendocrine Cancer | Glaucoma, Congenital | Budd-Chiari Syndrome | Crisponi Syndrome | Spinocerebellar Ataxia Type 5 | Leishmaniasis, Cutaneous | Brachial Plexus Neuropathy | Poretti-Boltshauser Syndrome | Primary Familial Brain Calcification | Combined Deficiency Of Factor V And Factor VIII | Cancer, Lung | Epidermolysis Bullosa Acquisita | Cerebellofaciodental Syndrome | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Choroideremia | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Filariasis | Spinocerebellar Ataxia Type 20 | GAPO Syndrome | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Parkinson Disease 6, Autosomal Recessive Early-onset | Congenital Adrenal Hyperplasia | Chondrodysplasia Punctata | Cholangitis | Wolff-Parkinson-White Syndrome | Neurodermatitis | Nance-Horan Syndrome | Rolandic Epilepsy | Astigmatism | Multiple Sclerosis, Secondary Progressive | Zygomycosis | Cholangiocarcinoma | Cockayne Syndrome | Asthma | Multiple Sclerosis, Chronic Progressive | Parvovirus B19 Infection | DiGeorge Syndrome | Osteitis | Chronic Granulomatous Disease, X-linked | Lafora Disease | Retinopathy Of Prematurity | Pseudohypoparathyroidism Type 1A | Antiphospholipid Syndrome | Polydactyly | Skin Papilloma | Cole-Carpenter Syndrome | Hepatic Steatosis | Lathosterolosis | Methylmalonic Aciduria And Homocystinuria, CblC Type | Lymphangioleiomyomatosis | Meconium Ileus | Hermansky-Pudlak Syndrome | Fontaine Progeroid Syndrome | Spinocerebellar Ataxia Type 2 | Kaposiform Hemangioendothelioma | Carcinoma, Squamous Cell | Cherubism | Pendred Syndrome | Systemic Mastocytosis | Werner's Syndrome | Fibrillation, Atrial | Erdheim-Chester Disease | Megalencephaly | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Ureteropelvic Junction Obstruction | Myofibrillar Myopathy | Hepatitis, Chronic | Angiodysplasia | Empyema | Homocystinuria | Hypopituitarism | Esthesioneuroblastoma | Hemangioendothelioma | Lipoma | Spinocerebellar Ataxia Type 27 | Otopalatodigital Syndrome Type 2 | Malaria | Endometriosis | Cutis Laxa | Cyst | Epidermolysis Bullosa Simplex, Localized | Hartsfield Syndrome | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Schizophrenia, Paranoid | Cancer, Bladder | Arthritis | Agoraphobia | Acrodermatitis Enteropathica | Trichomegaly | Cystinuria | Asthma, Nocturnal | Cataplexy | Osteogenesis Imperfecta Type IV | Cold-induced Sweating Syndrome | Woodhouse-Sakati Syndrome | Transcobalamin Deficiency | Krabbe Disease | Hepatitis, Alcoholic | Combined Pituitary Hormone Deficiency | Angiosarcoma Of The Breast | Giant Cell Glioblastoma | Hypohidrotic Ectodermal Dysplasia | Multiple Myeloma | Hyperostosis | Borderline Personality Disorder | Potocki-Shaffer Syndrome | Hepatitis E | Medulloblastoma | Avian Influenza | PHARC Syndrome | Chronic Periodontitis | Fanconi Syndrome | Meningioma | Rickets | Colitis, Microscopic | N-acetylglutamate Synthase Deficiency | Swine Influenza | Heterotaxy | CREST Syndrome | Congenital Heart Defects | Atelosteogenesis Type 1 | Congenital Nephrotic Syndrome | Neutrophilia | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Diabetic Macular Edema | Schuurs-Hoeijmakers Syndrome | Scabies | Porencephaly | Gigantism | Aldosteronism | Congenital Central Hypoventilation Syndrome | Pulmonary Sclerosing Hemangioma | Prolactinoma | Allergic Contact Dermatitis | Hoyeraal-Hreidarsson Syndrome | Tangier Disease | Paraganglioma | Lewy Body Dementia | Hypertensive Nephropathy | Leiomyoma | Optic Neuritis | Kidney Stones | Varices | Urofacial Syndrome | Cleidocranial Dysplasia | KBG Syndrome | Ehlers-Danlos Syndrome | Myotonic Disorders | Sick Sinus Syndrome 1 | Inflammatory Linear Verrucous Epidermal Nevus | Congenital Hereditary Endothelial Dystrophy Type II | Pseudomyxoma Peritonei | Vitamin K Deficiency | Panic Disorder | Dupuytren Disease | Pseudoexfoliation Syndrome | Mitochondrial Disease | Charcot-Marie-Tooth Disease Type 4D | Hyperinsulinemic Hypoglycemia | Sensory Neuropathy | Hypertensive Retinopathy | Menetrier Disease | Angioimmunoblastic T-cell Lymphoma | Neovascular Glaucoma | Herpes Simplex Dermatitis | Varicocele | Marshall-Smith Syndrome | Pontocerebellar Hypoplasia | Common Cold | Spinocerebellar Ataxia Type 15 | Aneurysm, Thoracic Aortic | Parapsoriasis | Pneumonia, Bacterial | Meniere's Disease | Babesiosis | Amelogenesis Imperfecta | Acute Anterior Uveitis | Kallmann Syndrome | Esophageal Adenocarcinoma | Milk Allergy | Non-epidermolytic Palmoplantar Keratoderma | Hemochromatosis | Hyperacusis | Treacher Collins Syndrome | Mountain Sickness | Scleritis | Esophagitis, Eosinophilic | Benign Hereditary Chorea | Familial Glucocorticoid Deficiency | Epidermolytic Palmoplantar Keratoderma | Jawad Syndrome | Inflammatory Joint Disease | Pemphigoid | Granuloma Annulare | Erythromelalgia | Chloridorrhea, Congenital | Myoclonic Atonic Epilepsy | Congenital Mirror Movements | Xeroderma Pigmentosum | Stickler Syndrome | Encephalopathy, Ethylmalonic | Hepatorenal Syndrome | Cohen Syndrome | Retinal Dystrophy | Placenta Previa | Fowler's Syndrome | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Rhizomelic Chondrodysplasia Punctata | Niemann-Pick Disease, Type B | Corticobasal Syndrome | Cancer, Kidney