Retinopathy Of Prematurity

About the Disease
Exudative Vitreoretinopathy 1, also known as retinopathy of prematurity, is related to exudative vitreoretinopathy and strabismus, and has symptoms including hyperoxia An important gene associated with Exudative Vitreoretinopathy 1 is FZD4 (Frizzled Class Receptor 4), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Zinc sulfate and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related phenotypes are premature birth and small for gestational age

Common Targets
EPHX2 | MTHFR | AGT | FECH | G7852 | LINC00200 | ADORA1 | ADORA2B | G4318 | LRP5 | F2 | ADORA2A | G4233 | KDR | NOS3 | FZD4 | ANGPT2 | TLR2 | SERPINE1 | HTRA1 | INSR | FLT3 | PDE5A | TRAP1 | G7422 | SCG3 | RET | TEK | beta-Adrenoceptor (nonspecified subtype) | CXCR3 | AGTR1 | NOS2 | F5 | GHR | SRPK1 | FPR2 | NLRP3 Inflammasome | G114548 | PTPN11 | KIT | TH | C3 | CFH | G7099 | EGLN1 | C2-AS1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | ANGPT1 | HMOX1 | Soluble guanylyl cyclase | CRP | TNFRSF1A | SAA1 | EPAS1 | MPO | HIF1A | ACE | RHOA | SAA2 | EGLN2 | BDNF | PDGFRB | C2 | EGLN3 | Integrin alphavbeta3 (vitronectin) receptor | CFB | TNFRSF1B

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