Disease

Retinopathy Of Prematurity

About the Disease
Exudative Vitreoretinopathy 1, also known as retinopathy of prematurity, is related to exudative vitreoretinopathy and strabismus, and has symptoms including hyperoxia An important gene associated with Exudative Vitreoretinopathy 1 is FZD4 (Frizzled Class Receptor 4), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Zinc sulfate and Zinc cation have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial, and related phenotypes are premature birth and small for gestational age

Common Targets
EPHX2 | MTHFR | AGT | FECH | G7852 | LINC00200 | ADORA1 | ADORA2B | G4318 | LRP5 | F2 | ADORA2A | G4233 | KDR | NOS3 | FZD4 | ANGPT2 | TLR2 | SERPINE1 | HTRA1 | INSR | FLT3 | PDE5A | TRAP1 | G7422 | SCG3 | RET | TEK | beta-Adrenoceptor (nonspecified subtype) | CXCR3 | AGTR1 | NOS2 | F5 | GHR | SRPK1 | FPR2 | NLRP3 Inflammasome | G114548 | PTPN11 | KIT | TH | C3 | CFH | G7099 | EGLN1 | C2-AS1 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | ANGPT1 | HMOX1 | Soluble guanylyl cyclase | CRP | TNFRSF1A | SAA1 | EPAS1 | MPO | HIF1A | ACE | RHOA | SAA2 | EGLN2 | BDNF | PDGFRB | C2 | EGLN3 | Integrin alphavbeta3 (vitronectin) receptor | CFB | TNFRSF1B

疾病靶点研报
Retinopathy Of Prematurity

Note: If you'd like to get a target analysis report for Retinopathy Of Prematurity, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Retinopathy Of Prematurity at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Conjunctivitis | Hypertension, Renovascular | Dysequilibrium Syndrome | Thyrotoxic Periodic Paralysis | Dementia, Vascular | Rhabdomyosarcoma | Restrictive Dermopathy | Disseminated Intravascular Coagulation | Lipid Metabolism Disorders | Autonomic Nervous System Disorders | Retinitis Pigmentosa 3 | Congenital Nystagmus | Hypercholesterolemia | Endophthalmitis | Long QT Syndrome Type 1 | Feingold Syndrome | Hemimegalencephaly | Hypophosphatasia | Meningitis | Acanthosis Nigricans | Hepatitis, Chronic | Takayasu's Arteritis | Vaginitis | Carcinoma, Squamous Cell | Acrocallosal Syndrome | NDH Syndrome | Cramp Fasciculation Syndrome | Thrombocythemia, Essential | Keratoconus | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Charcot-Marie-Tooth Disease | Nephropathy | Basal Ganglia Cerebrovascular Disease | Renal Oncocytoma | Alcoholism | Autosomal Recessive Congenital Ichthyosis | Miyoshi Myopathy | Presbyopia | Carcinoid Tumor | Central Retinal Artery Occlusion | Graves Disease | X-linked Sideroblastic Anemia | Autoimmune Polyendocrine Syndrome | Autism Spectrum Disorders | Asperger Syndrome | Epidermolytic Palmoplantar Keratoderma | Senior-Loken Syndrome | Heimler Syndrome | Jaundice, Obstructive | Episodic Ataxia | Infantile Nephropathic Cystinosis | Early Infantile Epileptic Encephalopathy 4 | Tracheal Disorders | Mountain Sickness | Persistent Hyperplastic Primary Vitreous | Chondromyxoid Fibroma | Long QT Syndrome Type 2 | Borderline Personality Disorder | Tetraplegia | Saethre-Chotzen Syndrome | Spinocerebellar Ataxia Type 3 | Spondyloperipheral Dysplasia | Pulmonary Stenosis | Hereditary Sensory And Autonomic Neuropathy | Kindler Syndrome | Congenital Torticollis | Nemaline Myopathy | Hyperbilirubinemia, Neonatal | Cardiofaciocutaneous Syndrome | Imerslund-Grasbeck Syndrome | Tinea Versicolor | Odonto-onycho-dermal Dysplasia | Kohlschutter-Tonz Syndrome | Neurofibromatosis-Noonan Syndrome | Hereditary Pyropoikilocytosis | Hemosiderosis | Anterior Segment Dysgenesis | Blepharophimosis Syndrome | Spinocerebellar Ataxia Type 7 | Pneumonia, Mycoplasma | Protein C Deficiency | Arrhythmogenic Right Ventricular Cardiomyopathy | Pelizaeus-Merzbacher Disease | Pre-eclampsia | Noonan Syndrome-like Disorder With Loose Anagen Hair | Esophagitis | Multicentric Carpotarsal Osteolysis Syndrome | Gastric Atrophy | Rothmund-Thomson Syndrome | Generalized Epilepsy With Febrile Seizures Plus | Dystonia | Anorchia | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Pseudohypoparathyroidism Type 1B | Sick Sinus Syndrome 1 | Metabolic Syndrome | Schindler Disease | Parkinson Disease 6, Autosomal Recessive Early-onset | Tyrosinemia | Acne Vulgaris | Thrombophlebitis | Infantile Liver Failure Syndrome 1 | Aspartylglycosaminuria | CREST Syndrome | Porphyria, Variegate | Congenital Myasthenic Syndrome | Persistent Mullerian Duct Syndrome | Primary Familial Brain Calcification | Torticollis | Keratoacanthoma | Congenital Diaphragmatic Hernia | Retinitis | Liver Diseases | Otopalatodigital Syndrome Type 2 | Creatine Deficiency Syndrome | Gangliosidosis | Polymyositis | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Alzheimer Disease, Late Onset | HANAC Syndrome | Sleep Apnea | Chronic Beryllium Disease | Diabetes Gestational | Diarrhea | Blastomycosis | Ischemia | Down Syndrome | Polycystic Liver | Stuttering | AIDS Dementia Complex | Hydronephrosis | Hyperlipidemia Type V | Hidradenitis Suppurativa | Hashimoto Thyroiditis | Renal Failure | Chondrodysplasia Punctata 2, X-linked Dominant | Snyder-Robinson Syndrome | Klippel-Feil Syndrome | Filariasis | Renal Hypomagnesemia 3 | Burn-McKeown Syndrome | Syndactyly | Meningococcal Infections | Pituitary Dwarfism | Gastritis, Atrophic | Coenzyme Q10 Deficiency | ACTH-independent Macronodular Adrenal Hyperplasia | Gerodermia Osteodysplastica | Gitelman Syndrome | Obsessive-compulsive Disorder | Glycogen Storage Disease Type 1 | Zygomycosis | Dysferlinopathy | Neurotoxicity | Marinesco-Sjogren Syndrome | Hyperhomocysteinemia | N-acetylglutamate Synthase Deficiency | Epidermolytic Ichthyosis, Annular | Aneurysm, Thoracic Aortic | Cryopyrin-associated Periodic Syndromes | Sensorineural Hearing Loss | Palmoplantar Keratoderma | Adenocarcinoma | Marfan Syndrome | Sclerosteosis 2 | Hypermetropia | Peeling Skin Syndrome, Acral Type | Meningioma | Acute Lung Injury | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Stuve-Wiedemann Syndrome | Becker Muscular Dystrophy | Growth Hormone Excess | Alagille Syndrome | Neurocutaneous Syndromes | Schizotypal Personality Disorder | Congenital Stromal Corneal Dystrophy | Liddle Syndrome | Juvenile Myelomonocytic Leukemia | Hartsfield Syndrome | Gaucher Disease | Brachydactyly | Glutaric Aciduria Type 3 | Creutzfeldt-Jakob Disease | Histoplasmosis | Adrenal Insufficiency | Motor Neuron Diseases | Carotid Artery Disease | Cole-Carpenter Syndrome | Depression | T-cell Leukemia | Membranous Nephropathy | Light Chain Amyloidosis | Angioedema, Acquired | Pantothenate Kinase-associated Neurodegeneration | Syncope | Myositis | Coloboma | Chromosome 9q34.3 Deletion Syndrome | Dupuytren Disease | Hyperuricemic Nephropathy, Familial Juvenile | Localized Scleroderma | Fraser Syndrome | Glucagonoma | Idiopathic Pulmonary Fibrosis | Ameloblastoma | Dystrophy, Cone-rod | Dent Disease | VACTERL/VATER Association | Dentinogenesis Imperfecta | Mevalonate Kinase Deficiency | Acute Motor Axonal Neuropathy | Huntington's Disease | Epidermolysis Bullosa Dystrophica | Renal Medullary Carcinoma | B-cell Chronic Lymphocytic Leukemia | Metabolic Diseases | Liver Failure | Lysosomal Acid Lipase Deficiency | Prader-Willi Syndrome | Leiomyoma | Myosin Storage Myopathy | Nemaline Myopathy 10 | Mycosis Fungoides | Avian Influenza | Oculocutaneous Albinism Type 1 | Lattice Corneal Dystrophy Type 1 | Intestinal Tuberculosis | Chordoid Glioma | Cholangitis | Lassa Fever | Myasthenia Gravis | Bernard-Soulier Syndrome | Mannosidase Deficiency Diseases | Gastrointestinal Disorders | Rhizomelic Chondrodysplasia Punctata | Congenital Absence Of Vas Deferens | Cervical Dystonia | Intracranial Hypertension | Intestinal Obstruction | Familial Hypobetalipoproteinemia | Cushing Syndrome | Microcephaly | High Molecular Weight Kininogen Deficiency | Anal Fissure | Hereditary Inclusion Body Myopathy | Myelitis, Transverse | Hypopigmentation | Neurodermatitis | Hereditary Mixed Polyposis Syndrome | Woodhouse-Sakati Syndrome | Follicular Dendritic Cell Sarcoma | Glioma | Dermatomyositis | Prune Belly Syndrome | PHARC Syndrome | Atelosteogenesis Type 1 | Lymphoma, Follicular | Contact Dermatitis | Lymphoproliferative Disorders | Toxoplasmosis | Craniopharyngioma | Neuromyotonia | Polymyalgia Rheumatica | Fascioliasis | Pituitary Stalk Interruption Syndrome | POEMS Syndrome | Esophageal Adenocarcinoma | Mitochondrial Disease | Abetalipoproteinemia | Familial Thoracic Aortic Aneurysm | Mucolipidosis | Osteomalacia | Dengue Shock Syndrome | Silicosis | Constipation | Craniolenticulosutural Dysplasia | ADNP Syndrome | Glutathione Synthetase Deficiency | Postpoliomyelitis Syndrome | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Congenital Adrenal Hyperplasia 1 | Granuloma Annulare | Turner's Syndrome | Cholesteryl Ester Storage Disease | Norrie Disease | Congenital Nephrotic Syndrome | Lamellar Ichthyosis | Distal Myopathy | Diastrophic Dysplasia | Retinoschisis | Klinefelter Syndrome | Hyperandrogenemia | Milk Allergy | Hepatitis B, Chronic | Pneumonia, Bacterial | Spinocerebellar Ataxia Type 10 | Branchiootorenal Syndrome | Peyronie's Disease | Muir-Torre Syndrome | Cholestasis | Maternally Inherited Diabetes And Deafness | Pyruvate Decarboxylase Deficiency | Oculopharyngeal Muscular Dystrophy | Relapsing Polychondritis | Homocystinuria | Hereditary Coproporphyria | Carney Triad | Metachondromatosis | Agnathia-Otocephaly Complex | Geleophysic Dysplasia | Multiple Hamartoma Syndrome | Hyperthyroidism | Schwannoma | Pulverulent Zonular Cataract | Macrophage Activation Syndrome | Noonan Syndrome | Goiter | Measles | Adrenomyeloneuropathy | Premature Ejaculation | Colitis, Microscopic | Anorexia Nervosa | Asthma, Nocturnal | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Exocrine Pancreatic Insufficiency | Schaaf-Yang Syndrome | Lissencephaly 2 | Tumoral Calcinosis | Diabetes Insipidus, Neurogenic | Alopecia | Triphalangeal Thumb-polysyndactyly Syndrome | Sleep Apnea, Central | Cryptosporidiosis | Withdrawal Syndrome | Budd-Chiari Syndrome | Kabuki Syndrome 2 | Smith-Magenis Syndrome | Lipoma | Bethlem Myopathy | Lateral Meningocele Syndrome | Blepharoconjunctivitis | Pseudohermaphroditism | Vulvovaginitis | IgA Nephropathy | Hyperinsulinism-hyperammonemia Syndrome | Viral Meningitis | Osteoporosis-pseudoglioma Syndrome | Persistent Fetal Circulation | Bruck Syndrome | Donnai-Barrow Syndrome | Congenital Primary Aphakia | Lyme Disease | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Polyarteritis Nodosa | Proximal Symphalangism | Diabetes | Hyperprolactinemia | Encephalopathy, Ethylmalonic | Pneumococcal Meningitis | Rubeosis Iridis | Encephalopathy | Spondyloepiphyseal Dysplasia Tarda, X-linked | Oligoastrocytoma | Primary Carnitine Deficiency | Diverticulitis | Glaucoma | Autosomal Recessive Bestrophinopathy | Gastroenteritis, Eosinophilic | Congenital Afibrinogenemia | Behavioral Variant Of Frontotemporal Dementia | Spinal And Bulbar Muscular Atrophy | Congenital Tufting Enteropathy | Smith-Kingsmore Syndrome | Neuroleptic Malignant Syndrome | Anosmia, Congenital | Parapsoriasis | Diabetic Nephropathy | Johanson-Blizzard Syndrome | Congenital Central Hypoventilation Syndrome | Headache | Congenital Adrenal Hyperplasia | Best Macular Dystrophy | Olmsted Syndrome | Meningioma, Benign | MELAS Syndrome | Tatton-Brown-Rahman Syndrome | Lesch-Nyhan Syndrome | Hyperinsulinemia | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Lymphangioma | Atrioventricular Septal Defect | AIDS | Myopia | Enlarged Vestibular Aqueduct | Congenital Hereditary Endothelial Dystrophy Type II | Bloom Syndrome | Tietze Syndrome | Familial Mediterranean Fever