Takayasu's Arteritis

About the Disease
Takayasu Arteritis, also known as aortic arch syndrome, is related to vasculitis and aortitis. An important gene associated with Takayasu Arteritis is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Adalimumab and Tofacitinib have been mentioned in the context of this disorder. Affiliated tissues include heart, bone and t cells, and related phenotypes are hyperhidrosis and fatigue

Common Targets
PTPN2 | SHANK1 | NR3C1 | AP4B1 | VCX3B | IL12RB1 | RIMBP3 | VPS8 | EEFSEC | NXF2 | CCHCR1 | IL12RB2 | MLX | RPS9 | PTK2B | G7124 | LOC285626 | PTPN22 | JAK1 | COLEC12 | MYH14 | TULP2 | ELN | IL12A | IL6R | G596 | DMXL2 | CRP | IL18 | IL23R | FGF14 | MYH7B | LGALS1 | IL12B | KLHL33 | HLA-B | ANXA8L1 | MYD88 | EHBP1L1

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