Carney Triad

About the Disease
Carney Triad, also known as gastric leiomyosarcoma, pulmonary chondroma, and extraadrenal paraganglioma, is related to paragangliomas 1 and pheochromocytoma. An important gene associated with Carney Triad is SDHC (Succinate Dehydrogenase Complex Subunit C), and among its related pathways/superpathways are "Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins." and glycolysis (BioCyc). Affiliated tissues include lymph node and lung, and related phenotypes are nausea and vomiting and fatigue

Common Targets
SDHC | SDHA

Note: If you'd like to get a target analysis report for Carney Triad, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Carney Triad at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Guttate Psoriasis | Osteochondroma | Open-angle Glaucoma | Juvenile Myelomonocytic Leukemia | Astrocytoma, Anaplastic | Loeys-Dietz Syndrome | Neurocysticercosis | Aplastic Anemia | Waardenburg Syndrome | C3 Glomerulopathy | Neurodermatitis | Neural Tube Defect | Nephroblastoma | Hemangioblastoma | Hamartoma | Meesmann Corneal Dystrophy | Joubert Syndrome | Fukuyama Congenital Muscular Dystrophy | Sialidosis | Melanocytic Nevus | Heimler Syndrome | Chronic Lymphocytic Leukemia | Spinocerebellar Ataxia Type 38 | Silver-Russell Syndrome | Trichothiodystrophy | Myoclonic Epilepsy With Ragged Red Fibers | Stickler Syndrome | Angioedema, Hereditary | Infantile Nephropathic Cystinosis | Treacher Collins Syndrome | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Okihiro Syndrome | Cushing Syndrome | Adenoid Cystic Carcinoma | Chudley-McCullough Syndrome | Prader-Willi Syndrome | Nephrosclerosis | CHOPS Syndrome | Bietti Crystalline Dystrophy | Retinitis Pigmentosa | Thrombophilia | Retinal Dystrophy | Papilledema | Empyema | Sleep Apnea | Mast Cell Leukemia | Cardiomyopathy, Restrictive | Coffin-Siris Syndrome | Essential Fructosuria | Situs Inversus | Asthma, Nocturnal | Anterior Segment Dysgenesis | Lactose Intolerance | Choriocarcinoma | Non-Hodgkin Lymphoma | Progressive Familial Intrahepatic Cholestasis | Cardiomyopathy, Hypertrophic | Pyruvate Carboxylase Deficiency Disease | Axenfeld-Rieger Syndrome | Bronchiolitis | Combined Malonic And Methylmalonic Acidemia | Thanatophoric Dysplasia | Salla Disease | Fibrodysplasia Ossificans Progressiva | Spinocerebellar Ataxia Type 42 | Sarcoidosis | Chloridorrhea, Congenital | Shock, Cardiogenic | Diabetes Insipidus, Neurogenic | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Keratosis, Seborrheic | Walker-Warburg Syndrome | Spinocerebellar Ataxia Type 5 | Oculopharyngeal Muscular Dystrophy | Mucolipidosis Type III | Pemphigoid | Gastroenteritis | Pneumonia, Mycoplasma | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Glioblastoma | B-cell Chronic Lymphocytic Leukemia | Fatty Aldehyde Dehydrogenase Deficiency | COACH Syndrome | Gallstones | Spinocerebellar Ataxia Type 16 | Galactosialidosis | Hypercalcemia | Glycogen Storage Disease Type 6 | Budd-Chiari Syndrome | Bulimia Nervosa | Peroxisomal Disorder | Small Lymphocytic Lymphoma | Nance-Horan Syndrome | Congenital Myasthenic Syndrome | Acute Anterior Uveitis | Myhre Syndrome | Megalencephaly | Esophageal Carcinoma | Epithelial-myoepithelial Carcinoma | Early Infantile Epileptic Encephalopathy 28 | Astrocytoma | Wolcott-Rallison Syndrome | Oculocutaneous Albinism Type 2 | Erythrokeratodermia Variabilis | Obesity, Morbid | Tremor | Usher Syndrome Type III | Impulse Control Disorder | Congenital Generalized Lipodystrophy | Crouzon Syndrome With Acanthosis Nigricans | Spermatocele | Hemolytic Uremic Syndrome | Chorea-acanthocytosis | Vogt-Koyanagi-Harada Syndrome | Chronic Beryllium Disease | IMAGe Syndrome | High Molecular Weight Kininogen Deficiency | Carbohydrate Metabolism Disorders | Hypoglycemia | Glycogen Storage Disease Type 1b | Sjogren Syndrome | Acne Vulgaris | Gangliosidosis | Fucosidosis | Rash | Bruck Syndrome | Intestinal Hypomagnesemia 1 | Hyperglycemia | Waardenburg Syndrome Type 2 | Arts Syndrome | Retinitis | Hartnup Disease | Carpenter Syndrome | Hypopigmentation | Pulmonary Veno-occlusive Disease | Epidermolysis Bullosa Simplex | Kabuki Syndrome | Hypotonia-cystinuria Syndrome | Marfan Syndrome | Adenosine Deaminase 2 Deficiency | Angiosarcoma | Myasthenia | Benign Hereditary Chorea | Melanoma | Behavioral Variant Of Frontotemporal Dementia | WAGR Syndrome | Nijmegen Breakage Syndrome | Fibrillation, Atrial | Zellweger Syndrome | Osteopathia Striata With Cranial Sclerosis | Hereditary Sensory And Autonomic Neuropathy | Fontaine Progeroid Syndrome | Growth Hormone Excess | Thalassemia, Beta | Familial Dysautonomia | Triphalangeal Thumb-polysyndactyly Syndrome | Miyoshi Myopathy | Gangliosidosis, GM1 | Ligneous Conjunctivitis | Charcot-Marie-Tooth Disease, Type 2 | Glomerulonephritis | Diabetic Neuropathy | Fanconi Syndrome | Muscle Wasting | Anthrax | Bronchitis, Chronic | Omenn Syndrome | Centronuclear Myopathy | Polymyositis | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Myocardial Infarction | Porphyria, Acute Intermittent | Presbyopia | Canavan Disease | Oculocutaneous Albinism Type 4 | MIRAGE Syndrome | Primary Hyperoxaluria | KBG Syndrome | Spondylocostal Dysostosis | Common Cold | Light Chain Amyloidosis | Esophagitis, Eosinophilic | Coffin-Lowry Syndrome | Ophthalmia, Sympathetic | Renal Tubular Acidosis | Mycosis Fungoides | Limb Girdle Muscular Dystrophy | Erythromelalgia | Uremia | Coronary Heart Disease | Dermatofibrosarcoma | Arthritis, Reactive | Cystinosis | X-linked Acrogigantism | Gigantism | Hyperlipidemia | Dowling-Degos Disease | Ovarian Hyperstimulation Syndrome | Distal Spinal Muscular Atrophy | Vitiligo | Mesothelioma, Malignant | Hemolytic Uremic Syndrome, Atypical | Takotsubo Cardiomyopathy | Overactive Bladder | Peyronie's Disease | Herpes Simplex Dermatitis | Periventricular Nodular Heterotopia | Trichuriasis | Spondyloarthritis | PHARC Syndrome | Conjunctivitis, Allergic | Rheumatoid Arthritis | Pearson Syndrome | Keratoconus | Kleine-Levin Syndrome | Cancer, Breast | Familial Partial Lipodystrophy | Palmoplantar Keratoderma | Learning Disability | Li-Fraumeni Syndrome | Microphthalmia | Agammaglobulinemia | Tetraplegia | Infantile Liver Failure Syndrome 1 | Postaxial Polydactyly | Chondromyxoid Fibroma | Influenza | Auriculocondylar Syndrome | Angioedema, Acquired | Lassa Fever | Tricho-hepato-enteric Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | Desmosterolosis | Charcot-Marie-Tooth Disease Type 2D | Coenzyme Q10 Deficiency | Gingivitis | Cancer, Bladder | Rift Valley Fever | Adrenoleukodystrophy, X-linked | Congenital Bilateral Absence Of Vas Deferens | Kashin-Beck Disease | Cranioectodermal Dysplasia | Primary Sclerosing Cholangitis | Oligoastrocytoma | Bethlem Myopathy | Cyst | Macrophagic Myofasciitis | Hairy Cell Leukemia | Diffuse Palmoplantar Keratoderma | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | CREST Syndrome | Arthritis | Dysfibrinogenemia | Allan-Herndon-Dudley Syndrome | Chromosome 8q21.11 Deletion Syndrome | Renal Failure | Leprosy | Eosinophilic Asthma | Progressive Familial Intrahepatic Cholestasis Type 1 | Skin Papilloma | Batten Disease | Epilepsy | Vulvovaginitis | Nicolaides-Baraitser Syndrome | Paronychia | Corneal Neovascularization | Benign Familial Infantile Seizures | Polycythemia | Glaucomatocyclitic Crisis | Dental Caries | GLUT1 Deficiency Syndrome | Hypoproteinemia, Hypercatabolic | 3-methylglutaconic Aciduria Type IV | Shprintzen-Goldberg Syndrome | Glomerulonephritis, Membranous | Schwartz-Jampel-Aberfeld Syndrome | Dyslexia | Pigment Dispersion Syndrome | Diffuse Mesangial Sclerosis | Antenatal Bartter Syndrome Type 1 | REM Sleep Behavior Disorder | Congenital Adrenal Hyperplasia 1 | Crisponi Syndrome | Chitayat Syndrome | POEMS Syndrome | Isovaleric Acidemia | Schaaf-Yang Syndrome | Hepatitis B, Chronic | Inflammatory Bowel Disease | Gastritis | Multiple Sclerosis, Relapsing-remitting | Alazami Syndrome | Spondylometaphyseal Dysplasia | Hydrops Fetalis | Wiedemann-Steiner Syndrome | Tyrosinemia Type 2 | Methemoglobinemia Type IV | Schnyder Crystalline Corneal Dystrophy | Palsy, Cerebral | Xeroderma Pigmentosum Variant Type | Down Syndrome | Dysmorphophobia | Vertigo | Ileitis | Pulmonary Stenosis | Acrocallosal Syndrome | Duchenne Muscular Dystrophy | Usher Syndrome Type IIC | Polycystic Kidney, Autosomal Recessive | Dystonia | Sarcoma, Endometrial Stromal | Pemphigus Foliaceus | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Charcot-Marie-Tooth Disease Type 4E | Gout | Cystinuria | Hereditary Spastic Paraplegia | T-cell Leukemia | Aneurysm, Abdominal Aortic | Pityriasis Rubra Pilaris | Hyperandrogenemia | Pseudohypoaldosteronism | Keratosis | Split Hand-foot Malformation | Cataract | Castleman Disease | Encephalopathy | Narcolepsy | Chordoma | Renal-hepatic-pancreatic Dysplasia | Hennekam Lymphangiectasia-lymphedema Syndrome | Thanatophoric Dysplasia Type 1 | Preaxial Polydactyly | Hereditary Pyropoikilocytosis | Persistent Fetal Circulation | Hypogammaglobulinemia | Extramammary Paget's Disease | Dysequilibrium Syndrome | Muckle-Wells Syndrome | Multiple Epiphyseal Dysplasia | Dubin-Johnson Syndrome | Melnick-Needles Syndrome | Episodic Ataxia Type 2 | Tracheal Disorders | Eczema | Xeroderma Pigmentosum | Pulmonary Tuberculosis | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Neuromuscular Disorders | Stiff-man Syndrome | Protein C Deficiency | Neurofibromatosis-Noonan Syndrome | Pachyonychia Congenita | Mitochondrial Myopathy | Dentinogenesis Imperfecta | Familial Isolated Hyperparathyroidism | Hashimoto Thyroiditis | Carotid Artery Disease | Endometritis | DICER1 Syndrome | Neonatal Progeroid Syndrome | Pierre Robin Syndrome | Fetal Akinesia Deformation Sequence | Muscular Dystrophy | Posterior Polar Cataract | Adenomyosis | Emery-Dreifuss Muscular Dystrophy | Hyperferritinemia-cataract Syndrome | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Guanidinoacetate Methyltransferase Deficiency | Scoliosis | Apraxia | Placenta Previa | Acute Lymphocytic Leukemia | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Autonomic Neuropathy | Mumps | Persistent Mullerian Duct Syndrome | Granuloma Annulare | Tatton-Brown-Rahman Syndrome | Ichthyosis | Gestational Trophoblastic Disease | TARP Syndrome | Pituitary Disorders | Erythema Multiforme | Combined Pituitary Hormone Deficiency | Peeling Skin Syndrome, Acral Type | Infertility | Infantile Neuroaxonal Dystrophy | Greenberg Dysplasia | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Strabismus | Spinocerebellar Ataxia Type 3 | T-cell Lymphoma, Subcutaneous Panniculitis-like | Imerslund-Grasbeck Syndrome | Sporadic Hemiplegic Migraine | Inflammatory Joint Disease | Acute Chest Syndrome | Sorsby Fundus Dystrophy | Wolfram Syndrome 2