Powered by AI technology, BDE-Bio combines massive literature, patent and comprehensive biological data to accurately screen and predict disease diagnosis and therapeutic targets / biomarkers. It can automatically generate target research reports with one click, making it an indispensable tool for pharmaceutical research and development.
BDE-Bio
TARGET PRECISE DISCOVERY
Product Introduction
BDE-Bio achieves precise screening and prediction of new targets by combining 24-hour continuous updates, massive literature texts, comprehensive biological databases, and large-scale multi-omics data, and can provide the basis and logic for target discovery.
1) Capture: 24-hour monitoring of Pubmed, 24 public databases (genecard, drugbank, pubchem, etc.), real-time inbound parsing.
2) Extraction: It can extract basic information about the target, protein structure, biological mechanism of the target, drug resistance of the target, disease correlation, etc.
3) Analysis: Summarize long content, generate reports with one click, recommend target points, etc.
Target Prediction
Predicting targets that can successfully enter the clinical trial stage and ensuring that lead compounds based on predicted targets can successfully break through the PCC stage within an estimated time frame.
Target-based Drug Prediction
Predicting the difficulty level of target-based drug development provides a basis for assessing the value of target exploration.
Disease-Related Target Prediction
Predicting key targets for specific diseases and provide a basis for drug development for rare diseases and difficult and complicated diseases.
Common Targets and Diseases
Targets
ABCB1 | ABCG2 | ACE2 | AHR | AKT1 | ALK | AR | ATM | BAX | BCL2 | BCL2L1 | BECN1 | BRAF | BRCA1 | CAMP | CASP3 | CASP9 | CCL5 | CCND1 | CD274 | CD4 | CD8A | CDH1 | CDKN1A | CDKN2A | CREB1 | CXCL8 | CXCR4 | DNMT1 | EGF | EGFR | EP300 | ERBB2 | EREG | ESR1 | EZH2 | FN1 | FOXO3 | HDAC9 | HGF | HMGB1 | HSP90AA1 | HSPA4 | HSPA5 | IDO1 | IFNA1 | IGF1 | IGF1R | IL17A | IL6 | INS | JUN | KRAS | MAPK1 | MAPK14 | MAPK3 | MAPK8 | MAPT | MCL1 | MDM2 | MET | MMP9 | MTOR | MYC | NFE2L2 | NLRP3 | NOTCH1 | PARP1 | PCNA | PDCD1 | PLK1 | PRKAA1 | PRKAA2 | PTEN | PTGS2 | PTK2 | RELA | SIRT1 | SLTM | SMAD4 | SOD1 | SQSTM1 | SRC | STAT1 | STAT3 | STAT5A | TAK1 | TERT | TLR4 | TNF | TP53 | TXN | VEGFA | YAP1
Diseases
Contact Dermatitis | Vogt-Koyanagi-Harada Syndrome | Pneumonia, Bacterial | Postpoliomyelitis Syndrome | Sleep Apnea, Central | Meesmann Corneal Dystrophy | Toxic Epidermal Necrolysis | Eccrine Porocarcinoma | Martsolf Syndrome | Amelogenesis Imperfecta | Blepharophimosis Syndrome | Esophagitis, Eosinophilic | Polycythemia Vera | Dengue Shock Syndrome | Subacute Sclerosing Panencephalitis | H Syndrome | Familial Pheochromocytoma-paraganglioma | Autonomic Nervous System Disorders | Chronic Mucocutaneous Candidiasis | Pericarditis | Follicular Dendritic Cell Sarcoma | T-cell Chronic Lymphocytic Leukemia | DEND Syndrome | Argininosuccinic Aciduria | Multisystemic Smooth Muscle Dysfunction Syndrome | Spinocerebellar Ataxia Type 27 | Communication Disorders | Hereditary Coproporphyria | Hyperandrogenemia | Major Depression | Hepatitis, Alcoholic | Bicuspid Aortic Valve | Corneal Dystrophy And Perceptive Deafness | Cardiospondylocarpofacial Syndrome | Pierre Robin Syndrome | N-acetylglutamate Synthase Deficiency | Retinal Telangiectasia | Chronic Myeloid Leukemia | Raine Syndrome | Heterotopic Ossification | Hypertrophy | Heart Septal Defects | Ellis-Van Creveld Syndrome | Sporadic Inclusion Body Myositis | Osteopetrosis | Rhabdomyosarcoma | Renal Dysplasia | Metabolic Syndrome | Hemangioma | 3-hydroxy-3-methylglutaric Aciduria | Autoimmune Autonomic Ganglionopathy | Pseudohypoparathyroidism Type 1C | Hydrocephalus | Infantile Spasm | Gigantism | Methylmalonic Acidemia | Vici Syndrome | Erythema Multiforme | Congenital Disorders Of Glycosylation | DOCK8 Immunodeficiency Syndrome | AIDS Dementia Complex | Pulmonary Alveolar Microlithiasis | Tyrosinemia Type 1 | Diabetic Nephropathy | Amblyopia | Glycogen Storage Disease Type 0 | Peeling Skin Syndrome, Acral Type | Parkinson's Disease | Hyperphenylalaninemia | Micropenis | Brenner Tumor | Neurocutaneous Syndromes | Oculopharyngeal Muscular Dystrophy | Erythropoietic Protoporphyria | Adenoma, Pituitary | Chronic Beryllium Disease | T-cell Leukemia | Tibial Muscular Dystrophy | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Hydronephrosis | Retinal Coloboma | Chiari Malformation Type I | Osteochondroma | Endometrial Hyperplasia | Glycogen Storage Disease Type 0, Muscle | Cryopyrin-associated Periodic Syndromes | Wolfram Syndrome 2 | Low Phospholipid Associated Cholelithiasis | Bernard-Soulier Syndrome | Spinocerebellar Ataxia Type 40 | Oral Lichen Planus | Early Infantile Epileptic Encephalopathy 4 | Retinal Dystrophy, Early-onset Severe | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Malonyl-CoA Decarboxylase Deficiency | Renal Tubular Acidosis | Mevalonate Kinase Deficiency | Waardenburg Syndrome Type 1 | Craniopharyngioma | Kallmann Syndrome | Bartsocas-Papas Syndrome | DICER1 Syndrome | Usher Syndrome Type IIC | Multiple Myeloma | Premature Ejaculation | Neurogenic Bladder | LRBA Deficiency | Genee-Wiedemann Syndrome | Preaxial Polydactyly | Chondrodysplasia Punctata 1, X-linked Recessive | Early Infantile Epileptic Encephalopathy 1 | Hypertension, Renovascular | Colitis, Microscopic | Lupus Erythematosus | Fetal Akinesia Deformation Sequence | Fontaine Progeroid Syndrome | Duane Retraction Syndrome | Heart Block | Hemosiderosis | Mumps | Mastitis | Hemoglobinopathies | Congenital Nephrotic Syndrome | Intracerebral Hemorrhage | Turner's Syndrome | LEOPARD Syndrome | Hydrolethalus Syndrome | Fetal And Neonatal Alloimmune Thrombocytopenia | Aspartylglycosaminuria | Niemann-Pick Disease, Type B | Immunoproliferative Disorders | Pseudohypoparathyroidism Type 1A | Carbamoyl Phosphate Synthetase I Deficiency | Asthma | Nephroblastoma | Pontocerebellar Hypoplasia | 3-methylglutaconic Aciduria Type I | Meningeal Melanocytoma | Vitamin B12 Deficiency | DRESS Syndrome | Congenital Sodium Diarrhea | Twin-to-twin Transfusion Syndrome | Polyomavirus Nephropathy | Benign Familial Neonatal Convulsions | Osteomyelitis | Charcot-Marie-Tooth Disease Type 2E | Aldosterone Deficiency | Maternally Inherited Diabetes And Deafness | Primary Progressive Aphasia | Hypertension | Hamartoma | Keratosis, Actinic | Still Disease | Usher Syndrome Type III | Angioedema, Hereditary | Chronic Leukemia | Carbonic Anhydrase VA Deficiency | Chronic Inflammatory Demyelinating Polyneuropathy | Inflammatory Myopathy | Progressive Familial Intrahepatic Cholestasis Type 1 | Lathosterolosis | Trismus-pseudocamptodactyly Syndrome | Holt-Oram Syndrome | Meningioma, Benign | Familial Digital Arthropathy-brachydactyly | Conduct Disorder | Vitamin K Deficiency | Enhanced S-cone Syndrome | Globozoospermia | Frank-ter Haar Syndrome | Epicondylitis | Spinal And Bulbar Muscular Atrophy | Dysgerminoma | Progressive Familial Intrahepatic Cholestasis | Chromosome 8q21.11 Deletion Syndrome | Neurofibromatosis Type 1 | Cushing Syndrome | Osteogenesis Imperfecta Type II | Pompe Disease | Recurrent Respiratory Papillomatosis | Diffuse Mesangial Sclerosis | Leishmaniasis, Cutaneous | Acute Coronary Syndrome | Impulse Control Disorder | Cryptorchidism | Pulverulent Zonular Cataract | Tonsillitis | Aphasia | HANAC Syndrome | Hyperhomocysteinemia | Idiopathic Pulmonary Fibrosis | Apert Syndrome | Compartment Syndrome | Tendinopathy | Batten Disease | Mitochondrial Disease | Macrophage Activation Syndrome | GAPO Syndrome | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Purpura, Thrombotic Thrombocytopenic | Sialidosis | Silicosis | Glycogen Storage Disease Type 4 | Acrodysostosis | Uveitis, Anterior | Cole-Carpenter Syndrome | ICF Syndrome | Avellino Corneal Dystrophy | Cystitis | Imerslund-Grasbeck Syndrome | Hypertension, Essential | Lymphopenia | Thymoma, Malignant | Carpal Tunnel Syndrome | Growth Hormone Excess | Juvenile Xanthogranuloma | Optic Nerve Diseases | Macrodactyly | Cryoglobulinemia | Pseudo-pseudohypoparathyroidism | Pontocerebellar Hypoplasia Type 7 | Spinal Cord Diseases | Syndactyly | Chloridorrhea, Congenital | Tardive Dyskinesia | Neurofibroma, Plexiform | Disseminated Intravascular Coagulation | Polycystic Ovary Syndrome | Leukoencephalopathy, Progressive Multifocal | Encephalocele | Chromosome 5q Deletion Syndrome | Dystonia Musculorum Deformans | Achondrogenesis | Charcot-Marie-Tooth Disease Type 3 | Stroke, Ischemic | Alopecia Areata | Angioimmunoblastic T-cell Lymphoma | Binge Eating Disorder | Persistent Mullerian Duct Syndrome | Lymphoma Lymphoblastic | Thrombosis | Gastroenteritis | Inflammatory Myofibroblastic Tumor | Spinocerebellar Ataxia Type 12 | Papilledema | Jawad Syndrome | Precocious Puberty | Cryptosporidiosis | X-linked Sideroblastic Anemia | Walker-Warburg Syndrome | Rubeosis Iridis | Diabetes Insipidus, Nephrogenic | Hemolytic Uremic Syndrome | Neonatal Progeroid Syndrome | Episodic Ataxia | Myoclonic Epilepsy With Ragged Red Fibers | Hemophagocytic Lymphohistiocytosis | Congenital Tufting Enteropathy | Multiple System Atrophy | Hemolytic Anemia | Chronic Kidney Disease | Anorexia Nervosa | Progressive Familial Intrahepatic Cholestasis Type 2 | NDH Syndrome | Blue Nevus | Micro Syndrome | Hepatitis C, Chronic | Congenital Central Hypoventilation Syndrome | CREST Syndrome | Mast Cell Leukemia | Hypertension, Renal | ACTH-independent Macronodular Adrenal Hyperplasia | Apparent Mineralocorticoid Excess Syndrome | X-linked Creatine Transporter Deficiency | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | CDKL5 Deficiency Disorder | Arthritis, Psoriatic | Glioma | VACTERL Association | Multiple Sclerosis, Primary Progressive | Hyperinsulinemia | Urticaria | Encephalitis, Tick-borne | Nemaline Myopathy | Chorea | Erdheim-Chester Disease | Congenital Nystagmus | Corneal Dystrophy | Rickets | Melnick-Needles Syndrome | Cholesteryl Ester Storage Disease | Tic Disorder | PASLI Disease | Esthesioneuroblastoma | Anodontia | Thrombotic Microangiopathy | Long QT Syndrome Type 1 | Esophageal Motility Disorders | Cri-du-chat Syndrome | Leishmaniasis, Visceral | Cutaneous Mastocytosis | Miyoshi Myopathy | Zellweger Syndrome | Narcolepsy | Mucolipidosis Type II | Niemann-Pick Disease, Type A | Crohn's Disease | Alveolar Capillary Dysplasia | Lymphangioleiomyomatosis | Tetraplegia | Cholestasis | Angiosarcoma | Coma | Stuttering | Charcot-Marie-Tooth Disease, Type 6 | Diabetes Insipidus, Neurogenic | Familial Isolated Hyperparathyroidism | Chudley-McCullough Syndrome | Acrocallosal Syndrome | Spinocerebellar Ataxia Type 7 | Spinocerebellar Ataxia Type 10 | Lymphoma, Follicular | Arthritis, Gouty | Schamberg Disease | Hypodontia | Lung Diseases | Essential Fructosuria | Lymphoproliferative Disease, X-linked | Periventricular Nodular Heterotopia | WAGR Syndrome | Presbyopia | Gilbert Syndrome | Liddle Syndrome | Fahr Disease | High Molecular Weight Kininogen Deficiency | Veno-occlusive Disease | Myopia | Left Ventricular Noncompaction | Seminoma | Frontotemporal Dementia | Wiskott-Aldrich Syndrome | Colitis | Amelanotic Melanoma | Hypermethioninemia | Retinal Diseases | Spinocerebellar Ataxia Type 23 | Osteoporosis-pseudoglioma Syndrome | Trichothiodystrophy | Leukocyte Adhesion Deficiency | Hypogonadism | Charcot-Marie-Tooth Disease, Type 1A | Pilomatrix Carcinoma | Alagille Syndrome | Lissencephaly 2 | Uremia | Pregnancy, Ectopic | Schistosomiasis | Beckwith-Wiedemann Syndrome | Ectopia Lentis, Isolated, Autosomal Recessive | Primrose Syndrome | Lactose Intolerance | Tendinitis | Branchiootorenal Syndrome | Deafness, Dystonia, And Cerebral Hypomyelination | Von Hippel-Lindau Disease | Gynecomastia | Epidermolysis Bullosa Dystrophica | Osteogenesis Imperfecta Type V | GATA2 Deficiency | Conn Syndrome | Hypoglycemia | Situs Inversus | Myelitis, Transverse | Congenital Afibrinogenemia | Asperger Syndrome | Withdrawal Syndrome | Rotor Syndrome | Charcot-Marie-Tooth Disease Type 4 | Alstrom Syndrome | Speech Disorders | Peripheral Neuropathy | Craniosynostosis | Conjunctivitis, Allergic | Renal Hypomagnesemia 3 | Craniofacial Dysostosis | Nephrocalcinosis | Persistent Truncus Arteriosus | Thrombocythemia, Essential | Lichen Planus | Hypotrichosis Simplex | Viral Meningitis | AIDS | Histiocytosis | Menkes Disease | Primary Sclerosing Cholangitis | Schindler Disease | Charcot-Marie-Tooth Disease Axonal Type 2N | Pemphigoid | Keloid | Liver Failure