Rhabdomyosarcoma

About the Disease
Rhabdomyosarcoma is related to embryonal rhabdomyosarcoma and rhabdomyosarcoma 2. An important gene associated with Rhabdomyosarcoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Disease and Prolactin Signaling. The drugs Morphine and Mechlorethamine have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, lymph node and t cells, and related phenotypes are homeostasis/metabolism and neoplasm

Common Targets
FOXO1 | LTK | BCR | ERBB3 | G3845 | LCK | NOS3 | DNA-Directed RNA Polymerase (nonspecified subtype) | G2064 | CYP1A1 | KDM3A | HDAC3 | BRD2 | HHAT | NCAM1 | Hedgehog Protein (nonspecified subtype) | G3480 | MUTYH | FLT3 | Ephrin Receptor (nonspecified subtype) | TWIST2 | LOC102724428 | PTCH1 | RET | ZEB2 | TSC2 | NUP93 | ABCC2 | CSF3R | WWP1 | ALDH3A1 | ROS1 | GATA6 | G7157 | IRX1 | ANKRD40 | ERCC2 | HES5 | EPHB4 | DICER1 | ARHGEF1 | Mitogen-Activated Protein Kinase (nonspecified subtype) | PDGFRA | MRC1 | NAT1 | TEK | MYOD1 | NSD1 | ACKR1 | GSTP1 | BMP8A | KIT | FGFR4 | RB1 | KDM3B | CYP3A5 | GPC3 | PAX5 | RICTOR | KMT2A | G472 | NF1 | DDR1 | JAK3 | ELMO1 | MGMT | KDM1A | BLK | G7099 | EPHB6 | BCOR | CYP2C9 | TGFB1 | LYN | SIK2 | TOP2A | ABL1 | DOCK2 | FRK | PARP2 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | NOTCH2 | DRD3 | XRCC1 | ARID1A | ALX3 | G1029 | ABCC1 | FYN | SIK1 | MAML1 | CHEK2 | CLPP | EPHA5 | CYP2B6 | PDGFRB | CSF1R | MSH2 | ITGA9 | SDHA | ABCC4 | BTK | MYCN | P4HTM | NRAS | TWIST1 | MPO | HDAC2 | G6714 | TGFB3 | ABCC3 | G5243 | G5347 | DMD | PIK3CA | KDM4B | DRD2 | CYP3A4 | CDK4 | DAXX | KDM6A | KDM5A | CYP2C19 | YES1 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | HCK | SMO | G142 | TOP1 | G2099 | PIK3CD | Tubulin | CSK | CYP2C18 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | CUBN | FGR | BRD4 | HDAC1 | DDR2 | SMARCAL1 | G4233 | KDM5B | CSF3 | KDM5A-GATAD1-EMSY chromatin complex | MAP2K1 | KDR | G7852 | FLT4 | FANCD2 | FLCN | GATA4

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