Cone-rod Dystrophy

About the Disease
Cone-Rod Dystrophy 2, also known as cone-rod dystrophy, is related to cone-rod dystrophy 3 and cone-rod dystrophy 16. An important gene associated with Cone-Rod Dystrophy 2 is CRX (Cone-Rod Homeobox), and among its related pathways/superpathways are Bardet-Biedl syndrome and Ciliopathies. The drugs Tocopherol and Acetylcysteine have been mentioned in the context of this disorder. Affiliated tissues include Eye, and related phenotypes are abnormality of retinal pigmentation and photophobia

Common Targets
DYNC2I2 | MYO7A | KCNV2 | SPATA7 | TMEM98 | ATXN7 | CNGA3 | REEP6 | SPG11 | GUCY2D | RARA | BRCA2 | CFAP418 | SNRNP200 | PRPH2 | CYP4V2 | SPTA1 | RPGRIP1 | CRX | ALPK1 | CERKL | ARL3 | NMNAT1 | SEMA6B | PDE6C | TOPORS | GUCA1A | IMPDH1 | DRAM2 | POC1B | MIR26A1 | RIMS2 | TULP1 | PDE6B | KIAA2026 | PRPF31 | ABCA4 | RLBP1 | MERTK | GUCA1B | SLC4A7 | THOC3 | ALMS1 | EYS | SEMA4A | ATP1A3 | RP1 | RAB28 | HK1 | PITPNM3 | CYP26A1 | IMPG2 | PROM1 | USH2A | CDHR1 | RDH12 | ADAM9 | C1QTNF5 | BEST1 | RPGR | PCARE | CRB1 | APC2 | RGR | TTC1 | ATF6 | CFAP410 | MFSD8 | CC2D2A | MIR129-1 | RP1L1 | CACNA1F | GNAT1 | AIPL1 | NR2E3 | TMEM126B | CEP78 | CNGB3 | CUBN

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