Disease

Amyloidosis

About the Disease
Amyloidosis, also known as amyloid disease, is related to amyloidosis, hereditary, transthyretin-related and immunoglobulin light chain amyloidosis. An important gene associated with Amyloidosis is TTR (Transthyretin), and among its related pathways/superpathways are Innate Immune System and Metabolism of proteins. The drugs Citalopram and Ibuprofen have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and kidney, and related phenotypes are no effect and no effect

Common Targets
G596 | CRBN | MFGE8 | PSEN1 | SNCA | TTR | LYZ | ABL1 | G3569 | HDAC6 | LECT2 | CTSS | Matrix Metalloproteinase (MMP) (nonspecified subtype) | NF-kappaB (NFkB) | DHODH | COMT | FERMT2 | G4137 | EIF2AK4 | SAA2-SAA4 | APCS | BACE1 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | DCX (DDB1-CUL4-X-box) E3 protein ligase complex | PDE1B | NPEPPS | MEFV | FPR2 | G836 | GPRC6A | B2M | NR3C1 | TNFRSF17 | APOA1 | GSN | CTSK | CDK8 | EIF2AK3 | OSMR | HPSE | CTSB | APP | SAA1 | Tubulin | G367 | SAA2 | TNFRSF1A | LGALS1 | NLRP12 | G7124 | Proteasome Complex

疾病靶点研报
Amyloidosis

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