Disease

Larsen Syndrome

About the Disease
Larsen Syndrome, also known as lrs, is related to desbuquois dysplasia 1 and multiple joint dislocations, short stature, and craniofacial dysmorphism with or without congenital heart defects. An important gene associated with Larsen Syndrome is FLNB (Filamin B), and among its related pathways/superpathways are Metapathway biotransformation Phase I and II and Glycosaminoglycan metabolism. Affiliated tissues include spinal cord, bone and kidney, and related phenotypes are depressed nasal bridge and hypertelorism

Common Targets
B3GAT3 | SLC26A11 | GZF1 | FLNB

疾病靶点研报
Larsen Syndrome

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